Results 151 to 160 of about 674,206 (305)

Reduced vascular leakage correlates with breast carcinoma T regulatory cell infiltration but not with metastatic propensity

open access: yesMolecular Oncology, EarlyView.
A mouse model for vascular normalization and a human breast cancer cohort were studied to understand the relationship between vascular leakage and tumor immune suppression. For this, endothelial and immune cell RNAseq, staining for vascular function, and immune cell profiling were employed.
Liqun He   +8 more
wiley   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

open access: yesMolecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson   +2 more
wiley   +1 more source

Thinking Styles: Analysis of its structural validity using adolescents' responses to the thinking styles inventory [PDF]

open access: yes, 2004
En su teoría del autogobierno mental, Sternberg afirma que tan importante como disponer de capacidades intelectuales es el modo en cómo se aplican éstas a las diferentes tareas, situaciones o contextos.
Bernardo, Ana   +10 more
core  

Comparison of Rwandan and American Followership Styles

open access: yes, 2014
Leadership research is plentiful and multifaceted yet followership, an essential component in leadership, attracts little research attention. This research paper measures followership styles in two cultural contexts: American and Rwandan.
Thomas, Debby
core   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

open access: yesMolecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia   +9 more
wiley   +1 more source

Thinking and Creating Styles in Students of Humanities and Social Sciences Applied Areas: Differences by Gender and Course

open access: yesPsicologia, 2010
The assessment of styles of thinking and creating can provide important information about the preferences of individuals and their behavior. The aim of this study was to investigate styles of thinking and creating on undergraduate students according ...
Tatiana de Cássia Nakano   +4 more
doaj  

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

open access: yesMolecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz   +15 more
wiley   +1 more source

Gaya Berpikir Siswa dalam Menganalisis Konsep Fisika melalui Grafik Kinematika [PDF]

open access: yes, 2017
Penelitian ini bertujuan untuk mengetahui gaya berpikir siswa dalam menganalisis konsep fisika melalui grafik pada konsep kinematika di SMA Negeri 2 Darul Makmur, Nagan Raya.
Muliana, E. (Endah)   +2 more
core  

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