Results 51 to 60 of about 216,704 (259)

Global asymptotic properties of third-order difference equations

Computers & Mathematics with Applications, 2004
The nonoscillatory solutions of \(\Delta(p_n\Delta(r_n\Delta x_n))+ q_n f(x_{n+p})= 0\), \(p\in \{0,1,2\}\), are classified under suitable conditions. In the case \(p= 1\) their generalized zeros and asymptotic properties are described by means of an energy function.
Došlá, Z., Kobza, A.
openaire   +2 more sources

On a Third‐Order System of Difference Equations with Variable Coefficients [PDF]

Abstract and Applied Analysis, 2012
We show that the system of three difference equations , , and , n ∈ ℕ0, where all elements of the sequences , , , n ∈ ℕ0, i ∈ {1,2, 3}, and initial values x−j, y−j, z−j, j ∈ {0,1, 2}, are real numbers, can be solved. Explicit formulae for solutions of the system are derived, and some consequences on asymptotic behavior of solutions for the case when ...
Stević, Stevo, Diblík, Josef, Iričanin, Bratislav, Šmarda, Zdeněk   +3 more
openaire   +4 more sources

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Oscillatory and asymptotically zero solutions of third order difference equations with quasidifferences [PDF]

Opuscula Mathematica, 2006
In this paper, third order difference equations are considered. We study the nonlinear third order difference equation with quasidifferences. Using Riccati transformation techniques, we establish some sufficient conditions for each solution of this ...
Ewa Schmeidel
doaj  

Revisiting Samuelson’s models, linear and nonlinear, stability conditions and oscillating dynamics

Journal of Economic Structures, 2021
In this work, we reconsider the dynamics of a few versions of the classical Samuelson’s multiplier–accelerator model for national economy. First we recall that the classical one with constant governmental expenditure, represented by a linear second-order
Fabio Tramontana, Laura Gardini
doaj   +1 more source

Dynamics and Bifurcation of $x_{n+1}=\frac{\alpha+\beta x_{n-2}}{A+Bx_{n}+C x_{n-2}}$

Journal of Mathematical Sciences and Modelling, 2021
In this paper, we study dynamics and bifurcation of the third order rational difference equation \begin{eqnarray*} x_{n+1}=\frac{\alpha+\beta x_{n-2}}{A+Bx_{n}+Cx_{n-2}}, ~~n=0, 1, 2, \ldots \end{eqnarray*} with positive parameters $\alpha, \beta, A, B ...
Mohammad Saleh, Batool Raddad
doaj   +1 more source

Class IIa HDACs forced degradation allows resensitization of oxaliplatin‐resistant FBXW7‐mutated colorectal cancer

Molecular Oncology, EarlyView.
HDAC4 is degraded by the E3 ligase FBXW7. In colorectal cancer, FBXW7 mutations prevent HDAC4 degradation, leading to oxaliplatin resistance. Forced degradation of HDAC4 using a PROTAC compound restores drug sensitivity by resetting the super‐enhancer landscape, reprogramming the epigenetic state of FBXW7‐mutated cells to resemble oxaliplatin ...
Vanessa Tolotto, Nicolò Gualandi, Ylenia Cortolezzis, Raffaella Picco, Monica Colitti, Francesca D'Este, Mariachiara Gani, Wayne W. Hancock, Giovanni Terrosu, Cristina Degrassi, Francesca Agostini, Claudio Brancolini, Luigi E. Xodo, Eros Di Giorgio   +13 more
wiley   +1 more source

On the stability of explicit finite difference schemes for a pseudoparabolic equation with nonlocal conditions

Nonlinear Analysis, 2014
A new explicit conditionally consistent finite difference scheme for one-dimensional third-order linear pseudoparabolic equation with nonlocal conditions is constructed.
Justina Jachimavičienė, Mifodijus Sapagovas, Artūras Štikonas, Olga Štikonienė   +3 more
doaj   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Antibiofilm activity of a chionodracine‐derived peptide by NMR‐based metabolomics of cell‐free supernatant of Acinetobacter baumannii clinical strains

FEBS Open Bio, EarlyView.
KHS‐Cnd peptide is able to impair biofilm formation and disaggregate mature biofilms in Acinetobacter baumannii clinical isolates. Differences in extracellular metabolites reflect changes in biofilm metabolism due to KHS‐Cnd treatment. Among the differentially represented extracellular metabolites upon KHS‐Cnd treatment, the significantly altered ...
Fernando Porcelli, Enrico Landi, Francesco Maiurano, Irene Paris, Rosanna Papa, Marco Artini, Laura Selan, Stefano Borocci, Francesco Buonocore, Esther Imperlini   +9 more
wiley   +1 more source