Results 101 to 110 of about 2,058,469 (292)

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

open access: yesMolecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan   +16 more
wiley   +1 more source

Watching My Mind Unfold versus Yours: An fMRI Study Using a Novel Camera Technology to Examine Neural Differences in Self-projection of Self versus Other Perspectives [PDF]

open access: yes, 2011
Self-projection, the capacity to re-experience the personal past and to mentally infer another person's perspective, has been linked to medial prefrontal cortex (mPFC).
Cabeza, R.   +3 more
core   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Real-time, subjective third-person experiences and psychiatric disorders in dignity, honor, and face cultures

open access: yesCurrent Research in Ecological and Social Psychology
Proceeding from the assumption that unusual experiences are sometimes extensions of the normal, we examine a rare phenomenological experience: namely, the real-time, subjective experience of being outside one’s body and looking at oneself as an outsider ...
Dov Cohen   +3 more
doaj   +1 more source

Drift and ownership towards a distant virtual body

open access: yesFrontiers in Human Neuroscience, 2013
In body ownership illusions participants feel that a mannequin or virtual body (VB) is their own. Earlier results suggest that body ownership over a body seen from behind in extra-personal space is possible when the surrogate body is visually stroked and
Ausias ePomes, Mel eSlater
doaj   +1 more source

Remembrance of things to come: a conversation between Zen and neuroscience on the predictive nature of the mind [PDF]

open access: yes, 2017
The notion of the brain as a predictive organ following Bayesian principles has been steadily gaining favor in neuroscience. This perspective, which has broad theoretical and applicative consequences, suggests also a novel way to look at the mind-body ...
Guareschi, Fausto Taiten   +1 more
core   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Open Problems in Relational Quantum Mechanics [PDF]

open access: yes, 2017
The Rovelli relational interpretation of quantum mechanics (RQM) is based on the assumption according to which the notion of observer-independent state of a physical system is to be rejected. In RQM the primary target of the theory is the analysis of the
Laudisa, Federico
core   +1 more source

Revisiting Mission‐Oriented Cancer Research to tackle the increasing burden of cancer in Europe–a policy perspective

open access: yesMolecular Oncology, EarlyView.
Translational cancer research and its implementation through competitively selected Comprehensive Cancer Centers across Europe should be the primary policy focus for addressing the increasing cancer burden in Europe and counteract the present main strategy to convert cancer to a chronic disease.
Manuel Heitor   +2 more
wiley   +1 more source

A motion capture study to measure the feeling of synchrony in romantic couples and in professional musicians [PDF]

open access: yes, 2016
The feeling of synchrony is fundamental for most social activities and prosocial behaviors. However, little is known about the behavioral correlates of this feeling and its modulation by intergroup differences.
Caecilia Charbonnier   +6 more
core   +2 more sources

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