Results 131 to 140 of about 17,767,631 (392)

Proceedings. First Assembly of the Latin-America and Caribbean Seismological Commission - LACSC

Earth Sciences Research Journal, 2014
The Latin-American and Caribbean region is an area with a very complex tectonic setting, where stress and strain generated by the interaction of several lithospheric plates is being absorbed.
Third Latin-American Congress of Seismol Third Latin-American Congress of Seismology
doaj  

Bridging trust gaps: Stakeholder perspectives on AI adoption in the United Kingdom NHS primary care

Digital Health
Objectives This study investigates the factors influencing artificial intelligence (AI) acceptance in the United Kingdom (UK) National Health Services (NHS) primary care across different stakeholder levels. It explores key barriers and enablers, focusing
Teresa Sides, Dhouha Kbaier, Tracie Farrell, Aisling Third   +3 more
doaj   +1 more source

Gut microbiota diversity is prognostic in metastatic hormone receptor‐positive breast cancer patients receiving chemotherapy and immunotherapy

Molecular Oncology, EarlyView.
In this exploratory study, we investigated the relationship between the gut microbiota and outcome in patients with metastatic hormone receptor‐positive breast cancer, treated in a randomized clinical trial with chemotherapy alone or chemotherapy in combination with immune checkpoint blockade.
Andreas Ullern, Kristian Holm, Nikolai Kragøe Andresen, Andreas Hagen Røssevold, Corinna Bang, Bjørn Naume, Johannes R. Hov, Jon Amund Kyte   +7 more
wiley   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

Laser hemorrhoidoplasty combined with blind hemorrhoidal artery ligation compared to Milligan–Morgan hemorrhoidectomy in patients with second and third degree piles; a prospective randomized study

, 2023
Amir Abdelhamid, Mohamed Elsheikh, Osama H. Abd‐Raboh   +2 more
openalex   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source

The Learning Strategy of Third Language (L3) University Students for the Korean Language: A Study of Chinese Students

, 2022
Luis Miguel Dos Santos
openalex   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

OTRA Based Voltage Mode Third Order Quadrature Oscillator [PDF]

, 2014
Rajeshwari Pandey, Neeta Pandey, Gurumurthy Komanapalli, Rashika Anurag   +3 more
openalex   +1 more source

Assessment of Clinical Criteria for Sepsis: For the Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).

Journal of the American Medical Association (JAMA), 2016
C. Seymour, V. Liu, T. Iwashyna, F. Brunkhorst, T. Rea, A. Scherag, G. Rubenfeld, J. Kahn, M. Shankar-Hari, M. Singer, C. Deutschman, G. Escobar, D. Angus   +12 more
semanticscholar   +1 more source