Results 161 to 170 of about 7,387,250 (229)

Role of third molars in mandibular fractures: a systematic umbrella review with updated meta-analysis. [PDF]

Front Oral Health
Omer SH, Mahmood MK, Abdulghafor MA, Amin YMM, Falguiere A, Lan R.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

Aortoduodenal syndrome caused by infrarenal abdominal aortic aneurysm: Evolution of CT findings and early imaging clues. [PDF]

Radiol Case Rep
Medina-Siosi AD.
europepmc   +1 more source

The C‐terminal domain of yeast Arginyltransferase1 is essential for its catalytic activity

FEBS Open Bio, EarlyView.
Arginyltransferase 1 (Ate1), a eukaryotic enzyme, catalyses arginylation, transferring arginine from tRNA‐Arg to the amino terminus of the target protein. Overexpression of Ate1 in yeast is lethal and is dependent on arginylation. This study elucidates how mutations in the cofactor‐binding and active site of Ate1 and truncation of its structural ...
Vikas Kumar Yadav, Shweta Shweta, Manisha Malhotra, Vikash Maurya, Akhilesh Kumar   +4 more
wiley   +1 more source

IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo

FEBS Open Bio, EarlyView.
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley   +1 more source

A Case of Robot-Assisted Radical Cystectomy for a Third Kidney Transplant Recipient. [PDF]

IJU Case Rep
Yamabe F, Kasahara M, Sakurabayashi K, Mitsui Y, Kobayashi H, Nakajima K.   +5 more
europepmc   +1 more source

Type I interferons modulate autophagy to shape gemcitabine response in pancreatic cancer cells

FEBS Open Bio, EarlyView.
Type I interferons differentially modulate autophagy and the response of pancreatic cancer cells to gemcitabine. IFNα2b stimulates autophagic flux and protects cells from gemcitabine‐induced cell death, contributing to chemoresistance. In contrast, IFNβ1a inhibits autophagosome formation and enhances gemcitabine‐induced cell death, resulting in ...
Lucy E. Bonilla, Martín M. Ledesma, Santiago A. Behr, Matías A. Pibuel, María L. Palanek, Daniel H. Grasso, Maria N. Garcia, Juan Garona, Silvina L. Lompardía, Elida Álvarez, Daniela L. Papademetrio   +10 more
wiley   +1 more source

Efficacy of Leukocyte Platelet Rich Fibrin (L-PRF) Versus L-PRF with βeta Tri-calcium Phosphate (β-TCP) Bone Graft in Mandibular Impacted Third Molar Surgery: A Split-Mouth Double Blinded Randomized Control Study. [PDF]

J Dent (Shiraz)
Stephenson GS, Pandyan DA, Chandran S, Narasimman D, Premkumar KK, Rajendran B, Pethuraj V.   +6 more
europepmc   +1 more source

Five‐Year Outcomes of Laparoscopic Sphincter‐Preserving Surgery for Rectal Cancer: A Prospective Study in Elderly Vietnamese Patients

Aging and Cancer, EarlyView.
This prospective study demonstrates that laparoscopic sphincter‐preserving surgery is feasible for elderly patients. While overall survival reaches 70% at 5 years, advanced T‐stage and the omission of neoadjuvant therapy significantly drive recurrence, highlighting the need for personalized geriatric protocols despite logistical challenges.
Huu Duc Ho, Quang Le, Ngoc Thach Tran, Van Viet Ung, Loc Vu   +4 more
wiley   +1 more source

Needle-to-bone safety margin of adrenaline auto-injectors in Japanese children: Impact of injection site variation. [PDF]

Pediatr Allergy Immunol
Kumagai C, Kawamoto N, Kaneyama T, Kadowaki S, Miwa Y, Kadowaki T, Kawamoto M, Ohnishi H.   +7 more
europepmc   +1 more source