Results 51 to 60 of about 7,387,250 (229)

Structural insights into an engineered feruloyl esterase with improved MHET degrading properties

open access: yesFEBS Letters, EarlyView.
A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa   +5 more
wiley   +1 more source

Towards the development of an integrative governance framework for the third sector : a theoretical review and analysis

open access: yes, 2006
This paper reviews the theoretical approaches taken in the governance literature in order to assess the relevance of their application to the third sector and to develop an integrative governance framework to help guide third sector organisations as they
Abraham, Anne, Millar, Murray E.
core  

Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system

open access: yesFEBS Letters, EarlyView.
Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley   +1 more source

The Impact of Cone Beam Computed Tomography on Surgical Decision-Making and Risk Assessment in Mandibular Third Molar Extractions: A Prospective Observational Diagnostic Study

open access: yesTomography
Aim: This study aimed to evaluate the impact of cone beam computed tomography (CBCT) on preoperative surgical decision-making and risk assessment for mandibular third molar (MM3) extractions in cases identified as high-risk by orthopantomography (OPG ...
Fatma Hande Aktemur Gürkan   +1 more
doaj   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Battle for Earth Summit

open access: yes, 1991
Environmental NGO position papers for UNCEDThe table of contents for this item can be shared with the requester. The requester may then choose one chapter, up to 10% of the item, as per the Fair Dealing provision of the Canadian Copyright ...
Third World Network
core   +1 more source

Third Molar Removal and Orofacial Pain: a Population-Based Survey [PDF]

open access: yeseJournal of Oral Maxillofacial Research, 2010
Objectives: The aim of the current study was to investigate whether there was a relationship between a history of third molar removal and the prevalence of orofacial pain in a sample of the general population.Material and methods: A survey was conducted ...
Laura J. Stevenson   +3 more
doaj  

Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation

open access: yesFEBS Letters, EarlyView.
Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz   +11 more
wiley   +1 more source

From crisis to mixed picture to phoney war: tracing third sector discourse in the 2008/9 recession [PDF]

open access: yes, 2012
The recession of 2008/09 threatened a crisis for the third sector and its beneficiaries. Amidst mounting concern for the sector’s future, national and horizontal infrastructure and government worked together to minimise the potential impacts.This ...
Parry, Jane   +2 more
core   +1 more source

Organizing the interface—Plasma membrane architecture and receptor dynamics in virus‐cell interactions

open access: yesFEBS Letters, EarlyView.
Plasma membranes contain dynamic nanoscale domains that organize lipids and receptors. Because viruses operate at similar scales, this architecture shapes early infection steps, including attachment, receptor engagement, and entry. Using influenza A virus and HIV‐1 as examples, we highlight how receptor nanoclusters, multivalent glycan interactions ...
Jan Schlegel, Christian Sieben
wiley   +1 more source

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