Results 51 to 60 of about 278,212 (299)
Molecular Oncology, EarlyView.Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura +19 more
wiley +1 more source
Interference Periods in Soybean Crop as Affected by Emergence Times of Weeds [PDF]
Planta Daninha, 2018 : Weeds emergence times modify competition with crops. Thus, the hypothesis was that the increase in weed emergence flow decreases the period prior to interference (PPI) in soybeans and increases the critical period of interference prevention (CPIP). The
R.R. ZANDONÁ +4 more
doaj +2 more sources
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
Animal, 2021 The phytol moiety in chlorophyll molecules acts as an agonist of peroxisome proliferator-activated receptor-α in monogastric animals. The current study aimed to clarify the effects of dietary supplementation with phytol on the plasma concentrations of ...
L.L. Ding +3 more
doaj +1 more source
Tumor B‐cell infiltration in platinum‐treated advanced muscle‐invasive urothelial carcinoma
Molecular Oncology, EarlyView.Bladder tumors with higher pretreatment memory B‐cell infiltration were linked to longer survival after cisplatin chemotherapy, but not carboplatin. These tumors also showed more organized immune structures (tertiary lymphoid structures) and a shared pro‐inflammatory B‐cell‐rich community, suggesting that memory B cells may help identify patients most ...
Konrad Stawiski +10 more
wiley +1 more source
ArtsThrough the coffin set of Tanethereret—dated to the first half of the 21st Dynasty—this article aims to underline the importance of analysing the masks and human features of ancient Egyptian yellow coffins and their value in disclosing new and important ...
Stefania Mainieri
doaj +1 more source
Middle Kingdom tombs of Asasif: archaeological fieldwork in 2017 [PDF]
Polish Archaeology in the Mediterranean, 2018 The recent works in the 2017 season at the North Asasif Necropolis have led to the discovery of Middle Kingdom burial assemblages, as well as funerary equipment dated to the Third Intermediate Period.
Patryk Chudzik
doaj +1 more source
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
More items of funerary linen from the Deir el-Bahari burialassemblages [PDF]
Polish Archaeology in the Mediterranean, 2016 A corpus of funerary linen was found in the 2012/2013 season in one of the rock tombscut in the cliff bordering the Tuthmosis III temple platform in Deir el-Bahari during the work ofthe Polish–Egyptian Archaeological and Conservation Mission of the ...
Aleksandra Hallmann
doaj +1 more source
FEBS Open Bio, EarlyView.This study investigated a novel WST‐8‐based assay for evaluating d‐Amino acid oxidase (DAO) inhibitors. We confirmed its effectiveness using known inhibitors and found that uremic toxins possess relatively weak inhibitory activity compared to existing drugs.
Kahoko Miyake +4 more
wiley +1 more source