Results 51 to 60 of about 249,323 (311)

Population pharmacokinetic modelling of amoxicillin in human breast milk—A contribution from the ConcePTION project

British Journal of Clinical Pharmacology, EarlyView.
Aims Amoxicillin, a widely used β‐lactam antibiotic, requires improved pharmacokinetic characterization during breastfeeding. This study used a population pharmacokinetic (PopPK) approach to model amoxicillin concentrations in breast milk, identify variability sources and estimate infant exposure, applying worst‐case scenarios.
Sarah Baklouti, Virginie Rigourd, Alice Panchaud, Hedvig Nordeng, Karel Allegaert, Pieter Annaert, Miao‐Chan Huang, Anaelle Monfort, Monia Guidi, Peggy Gandia   +9 more
wiley   +1 more source

Changes in Serum Concentrations of Bone Turnover Markers in Healthy Pregnant Women

International Journal of Clinical Practice, 2023
Background. Changes in bone metabolism during pregnancy have not received sufficient attention because of the lack of effective screening tools. Bone turnover markers (BTMs) could reflect the changes of bone metabolism. Currently, reference intervals for
Yiduo Zhang, Ruiying Li, Jing Zhang, Wenjie Zhou, Fan Yu   +4 more
doaj   +1 more source

Faktor yang Berhubungan dengan Kejadian Anemia pada Ibu Hamil Trimester III [PDF]

, 2019
The purpose of this study was to study the factors associated with the incidence of anemia in third trimester pregnant women. Research design This study was a cross sectional study The results of this study showed no significant relationship between age ...
., Romlah, Sari, Anjelina Puspita
core   +3 more sources

Tacrolimus exposure during pregnancy in kidney and liver transplantation recipients: A comparison between whole blood and plasma concentration‐to‐dose ratios

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus monitoring is generally performed in whole blood (WB). Most (>85%) of circulating tacrolimus is bound to red blood cells. During pregnancy, WB monitoring might be suboptimal because of physiological changes including increased plasma volume and decreased haematocrit.
Jildau R. Meinderts, Paola Mian, Frederike G. I. van Vilsteren, Karien M. H. van de Wetering, Jelmer R. Prins, Stefan P. Berger, Daan J. Touw, Margriet F. C. de Jong   +7 more
wiley   +1 more source

Do Major Pharmacovigilance Databases Support Evidence of Second Trimester NSAID and Third Trimester Paracetamol Fetotoxicity?

Pharmaceuticals
Background: Paracetamol and non-steroidal anti-inflammatory drugs (NSAIDs) are frequently used during pregnancy. Due to their fetotoxicity, NSAIDs are contraindicated during the third trimester.
Katarina Dathe, Carolin Benndorf, Simone Bergner, Christof Schaefer   +3 more
doaj   +1 more source

Physiological changes in iron and blood parameters during different pregnancy trimesters in pregnant women in Baghdad

Al-Mustansiriyah Journal of Science, 2018
Summary This work was carried out for four months in the province of Baghdad including many hospital in Bagdad during 1st of the November 2016 until 28 February 2017. 120 pregnant women included in the present study ranged in age from 14 - 42 years were
marwa thamir mohammed
doaj   +1 more source

Validation of the World Health Organization-5 well-being index; assessment of maternal well-being and its associated factors [PDF]

, 2015
Objective: The aim of this study was to validate the World Health Organization-5 Well-Being Index (WHO-5) in a sample of pregnant Iranian women, to explore the changes in maternal well-being from pregnancy to postpartum, and to determine the factors ...
Chaman, R., Khosravi, A., Mortazavi, F., Mousavi, S.-A.   +3 more
core  

Adnexal Torsion in the Third Trimester

Cureus
A 41-year-old woman presented with acute, severe left-sided abdominal pain and vomiting at 37 weeks' gestation. Her symptoms were attributed to renal colic, and she was admitted for supportive treatment. During her admission, she went into spontaneous labour.
Thiyagalingam, Subanhey, Petrosellini, Chiara, Mellon, Claire   +2 more
openaire   +2 more sources

Zuranolone: A case study in (regulatory) rush to judgement?

British Journal of Clinical Pharmacology, EarlyView.
Abstract Sage, in collaboration with Biogen, submitted a new drug approval for zuranolone for postpartum depression (PPD) and major depressive disorder (MDD) in December 2022. In August 2023, the US Food and Drug Administration granted approval for PPD but denied approval for MDD.
Lisa Cosgrove, Milutin Kostic, Barbara Mintzes, Gianna D'Ambrozio, Allen Shaughnessy   +4 more
wiley   +1 more source

IMPLEMENTASI KEPERAWATAN TERAPI RELAKSASI AUTOGENIK PADA IBU HAMIL PRIMIGRAVIDA TRIMESTER III DENGAN ANSIETAS DI DAERAH BINAAN IKEST MUHAMMADIYAH PALEMBANG

Masker Medika
Latar Belakang : Kehamilan merupakan kondisi perubahan citra tubuh dan peran dalam anggota keluarga. Ibu hamil biasanya menunjukkan respon psikologis dan emosional yang sama selama kehamilan diantaranya ambivalen, penerimaan, introversion, mood swings ...
Maratun Ulaa
doaj   +1 more source