Results 41 to 50 of about 214,622 (297)

Cyclic azapeptide CD36 ligand attenuates cardiac injury and reduces long‐chain fatty acid accumulation after myocardial ischemia–reperfusion in mice

FEBS Open Bio, EarlyView.
In a murine model of myocardial ischemia and reperfusion (MI/R), the CD36 azapeptide ligand MPE‐298 reduces cardiac injury and transiently lowers left ventricular long‐chain fatty acids (LCFAs) accumulation 3 h after reperfusion, accompanied by a decrease of oxidative stress and inflammation‐associated genes' expression in the heart and adipose tissue.
Jade Gauvin, Naghme Radmannia, David N. Huynh, Liliane Ménard, Caroline Daneault, Maïté Veilleux, Ahsanullah Ahsanullah, André C. Carpentier, William D. Lubell, Matthieu Ruiz, Huy Ong, Sylvie Marleau, Simon‐Pierre Gravel   +12 more
wiley   +1 more source

Familial colloid cyst of the third ventricle

Interdisciplinary Neurosurgery, 2018
Colloid cysts of the third ventricle are rare benign lesions. They can present as incidental finding on imaging or with symptoms of obstructive hydrocephalus. To date, 18 familial cases of colloid cyst have been reported.
Luke J. Weisbrod, Kyle A. Smith, Roukoz B. Chamoun   +2 more
doaj   +1 more source

Serum sodium disorder as a long-term complication after surgery for chordoid glioma of the third ventricle: A case report and literature review

Interdisciplinary Neurosurgery, 2021
Background: Chordoid glioma of the third ventricle is a rare tumor. Because of its special growth site and unique histomorphological characteristics, the clinical symptoms, imaging manifestations, operative difficulty, and postoperative complications may
GuangTang Chen, Zhonghua Li
doaj   +1 more source

Characterization of Clinical Phenotype to Glial Fibrillary Acidic Protein Concentrations in Alexander Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To determine the concentration of glial fibrillary acidic protein (GFAP) in cerebrospinal fluid (CSF) and plasma in Alexander disease (AxD) and whether GFAP levels are predictive of disease phenotypes. Methods CSF and plasma were collected (longitudinally when available) from AxD participants and non‐AxD controls.
Amy T. Waldman, Asako Takanohashi, Joshua Y. Joung, Geraldine W. Liu, Kaley Arnold, Amy Pizzino, Walter Faig, Sarah Woidill, Sona Narula, Adeline L. Vanderver   +9 more
wiley   +1 more source

PATH-38. ROSETTE-FORMING GLIONEURONAL TUMOR IS DEFINED BY FGFR1 ACTIVATING ALTERATIONS WITH FREQUENT ACCOMPANYING PI3K AND MAPK PATHWAY MUTATIONS [PDF]

, 2019
BACKGROUND Rosette-forming glioneuronal tumor (RGNT) is an uncommon CNS tumor originally described in the fourth ventricle characterized by a low-grade glial neoplasm admixed with a rosette-forming neurocytic component.
Aghi, Manish, Ann Oberheim-Bush, Nancy, Banerjee, Anu, Bannykh, Serguei, Berger, Mitchel, Bollen, Andrew, Born, Donald, Brathwaite, Carole, Buerki, Robin, Butowski, Nicholas, Calixto-Hope, Lucas, Chamyan, Gabriel, Chang, Susan, Clarke, Jennifer, Cooney, Tabitha, Devine, Patrick, Fata, Cynthia, Grafe, Marjorie, Grenert, James, Guo, Hua, Gupta, Nalin, Hervey-Jumper, Shawn, Hofmann, Jeffrey, Jin, Lee-way, Khatib, Ziad, Kleinschmidt-DeMasters, Bette, Kline, Cassie, Lechpammer, Mirna, Lee, Han, Lee, Julieann, Maher, Ossama, McDermott, Mike, Onodera, Courtney, Pekmezci, Melike, Pelaez, Liset, Perry, Arie, Phillips, Joanna, Raffel, Corey, Samuel, David, Scharnhorst, David, Sloan, Emily, Solomon, David, Sun, Peter, Taylor, Jennie, Theodosopoulos, Philip, Tihan, Tarik, Torkildson, Joseph, Van Ziffle, Jessica, Vogel, Hannes, Wood, Matthew   +49 more
core  

Value of MRI Outcomes for Preventive and Early‐Stage Trials in Spinocerebellar Ataxias 1 and 3

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To examine the value of MRI outcomes as endpoints for preventive and early‐stage trials of two polyglutamine spinocerebellar ataxias (SCAs). Methods A cohort of 100 participants (23 SCA1, 63 SCA3, median Scale for the Assessment and Rating of Ataxia (SARA) score = 5, 42% preataxic, and 14 gene‐negative controls) was scanned at 3T up ...
Thiago J. R. Rezende, Emilien Petit, Young Woo Park, Sophie Tezenas du Montcel, James M. Joers, Jonathan M. DuBois, H. Moore Arnold, Michal Povazan, Ipek Özdemir, Guita Banan, Romain Valabregue, Philipp Ehses, Jennifer Faber, Chiadi U. Onyike, Peter B. Barker, Jeremy D. Schmahmann, Eva‐Maria Ratai, Sub H. Subramony, Thomas H. Mareci, Khalaf O. Bushara, Henry Paulson, Thomas Klockgether, Alexandra Durr, Tetsuo Ashizawa, Christophe Lenglet, Gülin Öz, READISCA Investigators   +26 more
wiley   +1 more source

Third Ventricle Enlargement in Neonates with Trisomy 21

Pediatric Neurology Briefs, 2006
Measurements of routine head sonographic scans of 57 term infants with trisomy 21 born between 2000 and 2005 were performed within 7 days after birth and were compared with scans of 21 randomly selected, healthy, term infants without trisomy 21 at Shaare
J Gordon Millichap
doaj   +1 more source

The application of ultrasound in neuroendoscopic procedures: first results with the new tool »NECUP-2« [Upotreba ultrazvuka u neuroendoskopskim procedurama: prvi rezultati s novim uređajem »NECUP-2«] [PDF]

, 2011
In this paper, our experience with originally constructed Neurosurgical Endoscopic Contact Ultrasound Probe »NECUP-2« in neuroendoscopy is reported. Between June 1997 and June 2007, 132 neuroendoscopic procedures have been performed: 102 endoscopic thrid
Jednačak, Hrvoje, Klarica, Marijan, Miklić, Pavle, Mrak, Goran, Paladino, Josip, Vukić, Miroslav, Štimac, Tihomir   +6 more
core  

Will the real ventricular architecture please stand up? [PDF]

, 2017
Ventricular twisting, essential for cardiac function, is attributed to the contraction of myocardial helical fibers. The exact relationship between ventricular anatomy and function remains to be determined, but one commonly used explanatory model is the ...
Hoffman, Julien IE
core   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source