Results 61 to 70 of about 3,626,687 (274)

Effects of inner ear abnormalities on middle ear mechanics: Findings from adults with MD and LVAS

Brazilian Journal of Otorhinolaryngology
Objective: To evaluate the clinical significance of WAI as a predictive marker for MD and LVAS among adults. Methods: Participants included 110 ears with MD, 18 ears with LVAS, and 92 normal ears (control group) recruited from clinical audiology settings.
Wen Jiang, Yi Mu, Huan Lin, Chanfeng Shen, Huiying Zhang, Fei Zhao, Yuehua Qiao, Xuanyi Li, Wen Liu   +8 more
doaj   +1 more source

Remediation, Medievalism, and Empire in T. W. Camm’s ‘Jubilee of the Nations’ Window at Great Malvern Priory

19, 2020
T. W. Camm’s ‘Jubilee of the Nations’ window created for Great Malvern Priory in 1887 combines a vision of late-Victorian imperial ideology with a narrative of Queen Victoria’s reign.
Jim Cheshire
doaj   +2 more sources

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Evolution‐guided yeast complementation reveals functional differences in human PSPH variants

FEBS Open Bio, EarlyView.
Ancient genomes can help guide which human genetic variants are tested experimentally. This study applies that idea to PSPH, a gene involved in serine biosynthesis, and uses high‐throughput yeast complementation to compare variant function. The findings reveal measurable differences among selected alleles and illustrate the value of evolution‐guided ...
Mauricio Campa‐Álvarez, Diana Ascencio, Miguel Vallebueno‐Estrada, Eduardo González‐Orozco, Christian Eduardo Martínez‐Guerrero, Rafael Montiel, Alexander DeLuna   +6 more
wiley   +1 more source

Transcatheter closure of symptomatic aortopulmonary window in an infant [PDF]

, 2008
An aortopulmonary window is a rare congenital cardiac defect. In the majority of symptomatic neonates and infants, primary surgical repair is the treatment of choice.
Brockmeier, Konrad, Sreeram, Narayanswami, Pillekamp, Frank, Hannes, Tobias, Koch, Daniel   +4 more
core  

Air–Bone Gap in Meniere’s Disease: A Case Series and Literature Review

Audiology Research
Background/Objectives: An air–bone gap (ABG) on audiometry is usually secondary to a conductive hearing loss. However, persistent and repeatable ABGs on audiometry in the absence of external or middle ear pathology is thought to arise from inner ear ...
Arun Pajaniappane, Nilesh Parekh, Anita Wong   +2 more
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source

An experimental and numerical investigation of the thermal performance of phase change materials in different triple-glazed window configurations

International Journal of Thermofluids
Phase Change Materials (PCM) may be excellent thermal insulation due to their poor conductivity and high heat capacity. Researchers are adding PCM to windows. This integration modifies internal surface temperatures and delays peak temperatures to improve
Mina A. Nsaif, Jalal M. Jalil, Mounir Baccar   +2 more
doaj   +1 more source

Understanding and Mitigating the Risk of Accelerated Biological Aging in Survivors of Cancer: A Scoping Review

Aging and Cancer, EarlyView.
Cancer treatment is associated with measurable acceleration of biological aging across epigenetic, telomere, senescence, and immune biomarkers. However, biomarker validation and interventional strategies remain limited, especially in hematologic malignancies, underscoring the need for standardized multi‐omic aging assessments and adequately powered ...
Moataz Ellithi, Emily Herdman, Danielle Westmark, Vijaya R. Bhatt   +3 more
wiley   +1 more source