Results 121 to 130 of about 10,425,062 (302)

The VHL tumor suppressor at the crossroad of protein folding, aggregation, and cancer

open access: yesMolecular Oncology, EarlyView.
Mutations, environmental stress, and chaperone dysfunction can destabilize pVHL, promoting its conversion from the native folded state into amyloid‐like assemblies. This transition may contribute to protein storage, cell dormancy, survival, and drug resistance.
Lara Abad   +2 more
wiley   +1 more source

Security Theories of Third World

open access: yesVestnik RUDN. International Relations, 2016
This article analyzes the security studies in the “Third World”. The evolution of the conceptual apparatus in the field of security studies and in the understanding of the “Third World” is given.
Alexandra Victorovna Khudaykulova
doaj  

Denial and Distancing in Discourses of Development: shadow of the ‘Third World’ in New Zealand

open access: yes, 2012
Anxieties about development in New Zealand show up in a deep-rooted fear of the ‘Third World’ in the country. We examine how the term ‘Third World’ is deployed in media discourses in economic, social and environmental contexts and how this deployment ...
Munshi, Debashish, Kurian, Priya A.
core   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Europe Looks at the Third World: The EEC-NGO Experience

open access: yes, 2009
The protectionist policy of the European Economic Community (EEC) has created a negative image for the regional economic grouping in the eyes of Third World countries. For the EEC such a policy is needed to foster regional sufficiency and economic growth.
Encarnacion, Teresa
core  

Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies

open access: yesFEBS Open Bio, EarlyView.
We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli   +8 more
wiley   +1 more source

Real world perspective of coronary chronic total occlusion in third world countries: A tertiary care centre study from northern India. [PDF]

open access: yesIndian Heart J, 2021
Vemuri KS   +17 more
europepmc   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

The C‐terminal region of KIF26B is indispensable for nephron progenitor condensation and kidney formation in mice

open access: yesFEBS Open Bio, EarlyView.
KIF26B plays an important role in kidney development. We engineered mice lacking the C‐terminal region of KIF26B and found severe kidney defects, including bilateral renal agenesis, similar to full Kif26b knockout mice. The mutation disrupted nephron progenitor condensation and reduced Gdnf‐Wnt11 signaling, showing that the KIF26B C‐terminal region is ...
Yuta Yamamura   +19 more
wiley   +1 more source

Fetal Cardiac Interventions-Polish Experience from "Zero" to the Third World Largest Program. [PDF]

open access: yesJ Clin Med, 2020
Debska M   +8 more
europepmc   +1 more source

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