Results 111 to 120 of about 218 (188)

Brain reward function in young people with cannabis use disorder: A functional magnetic resonance imaging study

Addiction, EarlyView.
Abstract Background and Aims Cannabis use disorder (CUD) affects ~50 million people globally. Neuroscientific theories suggest that a blunted neural response to non‐drug rewards is a hallmark of substance use disorders; however, this remains untested in CUD. The current study tested whether brain reward system responses to the anticipation and feedback
Martine Skumlien, Lisa‐Marie Greenwood, Arush Honnedevasthana Arun, Isabella Goodwin, Anastasia Paloubis, Tribikram Thapa Rana, Marianna Quinones Valera, Eugene McTavish, Gabrielle Abbott, Suraya Dunsford, Antonio Verdejo‐Garcia, Jessica Ramamurthy, Mark M. Schira, Nadia Solowij, Chao Suo, Valentina Lorenzetti   +15 more
wiley   +1 more source

Beyond abstinence: Redefining success in cannabis use disorder treatment

Addiction, EarlyView.
Abstract Background Over two decades of pharmacotherapy research has yet to yield a consistently effective medication for cannabis use disorder (CUD), in part because clinical trials have frequently prioritized abstinence as a primary or key endpoint.
Tobias B. Atkin, Frances R. Levin, John Mariani, Christina A. Brezing   +3 more
wiley   +1 more source

Psychological change processes in alcohol use disorder: A qualitative study of 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT) with cognitive behavioural therapy

Addiction, EarlyView.
Abstract Background and aims This study qualitatively explored psychological change processes as described by participants and therapists within a phase 2a clinical trial evaluating the safety, tolerability, and preliminary efficacy of a single dose of intranasal 5‐methoxy‐N,N‐dimethyltryptamine (5‐MeO‐DMT; BPL‐003) administered alongside psychological
Mathieu Seynaeve, Fiona Dunbar, Anna O. Ermakova, Luke Mitcheson, James J. Rucker, Anthony Cleare, John Marsden   +6 more
wiley   +1 more source

From allostasis to addiction: Cortisol dysregulation, daily stress and relations with 9‐year alcohol and substance use disorder severity in community adults

Addiction, EarlyView.
Abstract Background and aims Diurnal cortisol dysregulation and daily stressor severity may jointly forecast long‐term alcohol use disorder (AUD) and substance use disorder (SUD) severity, yet most evidence is cross‐sectional and relies on single cortisol indices.
Nur Hani Zainal, Natalia Van Doren
wiley   +1 more source

Changes in the transition from cannabis use to use disorder by decade of first use: Findings from the Australian National Mental Health and Wellbeing surveys

Addiction, EarlyView.
Abstract Background and aims As cannabis becomes increasingly accessible and products more potent, it is critical that we understand how this may impact the risk of transitioning from cannabis use to cannabis use disorder (CUD). We aimed to examine whether the risk and speed of transition from cannabis use to CUD differ by decade of first cannabis use.
Jack Wilson, Siobhan O'Dean, Christina Marel, Olivia Dobson, Matthew Sunderland, Steph Kershaw, Tara Gückel, Emma Krogh Devine, Tim Slade, Maree Teesson, Emily Stockings   +10 more
wiley   +1 more source

The association between chronic pain and non‐fatal overdose in people who inject drugs: Longitudinal cohort study in Montreal, Canada, 2017 to 2025

Addiction, EarlyView.
Abstract Background and aims The prevalence of chronic pain is elevated among people who inject drugs. Chronic pain may motivate drug use, potentially increasing the risk of non‐fatal overdose. We aimed to estimate the association between chronic pain and non‐fatal overdose in people who inject drugs.
Sarah Larney, Geng Zang, Harika Dasari, M. Gabrielle Pagé, Farzaneh Vakili, Adelina Artenie, Valérie Martel‐Laferrière, Nanor Minoyan, Sasha Udhesister, Julie Bruneau   +9 more
wiley   +1 more source

The bidirectional predictive association between methamphetamine use and depression

Addiction, EarlyView.
Abstract Background and aims Co‐occurrence of methamphetamine dependence and depression is high, though the direction of this temporal relationship is unclear. We investigated the direction of the temporal relationship between methamphetamine use and depression.
Lucy T. Tran, Philip J. Clare, Louisa Degenhardt, Dan I. Lubman, Michael Berk, Gregory Carter, Shalini Arunogiri, Alyna Turner, Olivia M. Dean, Peter Kelly, Rebecca McKetin   +10 more
wiley   +1 more source

Clinical features of mental imagery in substance use disorders: A mixed‐methods analysis

Addiction, EarlyView.
Abstract Aims To characterise the frequency, features and content of craving‐related mental imagery among people seeking treatment for substance use disorders (SUDs); examine within‐session change in self‐reported craving following imagery elicitation; and explore perceived links with autobiographical memory, behavioural, cognitive and emotional ...
Gemma Scott, Tim Meynen, Francesca Small, Luke Mitcheson, Elizabeth Appiah‐Kusi, William Barber, Colette Hirsch, John Marsden   +7 more
wiley   +1 more source

Does smartphone addiction exist? A critical evaluation of the validity of behavioural addiction symptoms in problematic smartphone use

Addiction, EarlyView.
Abstract Background The current debate raises the question of whether “smartphone addiction” really exists and whether the phenomenon can be considered as a distinct, clinically relevant disorder. This question is examined from three perspectives: 1) the terminology and definition of the problematic behaviour, 2) the evidence of clinical relevance, the
Elisa Wegmann, Silke Behrendt, Janna Cousijn   +2 more
wiley   +1 more source

Peri‐operative management of patients having day surgery: a consensus statement from the Association of Anaesthetists, British Association for Day Surgery and the Association of Paediatric Anaesthetists, Great Britain and Ireland

Anaesthesia, EarlyView.
Summary Introduction Day surgery is now recognised widely as being a vital component of modern healthcare delivery with overall day surgery rates in the UK now > 85%. Day surgery offers an enhanced experience for patients with reduced risk of postoperative complications (e.g.
Craig R. Bailey, David Bunting, Lindsay Hudman, Shivan Kanani, Kirstin May, Catalina Stendall, Rachel Tibble, Allan Xu, Matthew D. Wiles   +8 more
wiley   +1 more source