Results 31 to 40 of about 669,227 (261)

The Nutritional Quality of Commercially Bred Yellow Mealworm (Tenebrio molitor) Compared to European Union Nutrition Claims

open access: yesInsects
Due to its potential as a sustainable protein source, the industrial relevance of Tenebrio molitor, known as yellow mealworm, is set to increase substantially.
Isabelle Noyens   +4 more
doaj   +1 more source

The neural crest‐associated gene ERRFI1 is involved in melanoma progression and resistance toward targeted therapy

open access: yesMolecular Oncology, EarlyView.
ERRFI1, a neural crest (NC)‐associated gene, was upregulated in melanoma and negatively correlated with the expression of melanocytic differentiation markers and the susceptibility of melanoma cells toward BRAF inhibitors (BRAFi). Knocking down ERRFI1 significantly increased the sensitivity of melanoma cells to BRAFi.
Nina Wang   +8 more
wiley   +1 more source

Methylation biomarkers can distinguish pleural mesothelioma from healthy pleura and other pleural pathologies

open access: yesMolecular Oncology, EarlyView.
We developed and validated a DNA methylation–based biomarker panel to distinguish pleural mesothelioma from other pleural conditions. Using the IMPRESS technology, we translated this panel into a clinically applicable assay. The resulting two classifier models demonstrated excellent performance, achieving high AUC values and strong diagnostic accuracy.
Janah Vandenhoeck   +12 more
wiley   +1 more source

BEYOND CONSOLIDATING POWER: THE LOGIC AND ADAPTABILITY OF POLITICAL PURGES IN STALIN’S SOVIET UNION, SADDAM’S IRAQ, AND THE ASSAD’S SYRIA

open access: yesگۆڤارا زانستێن مرۆڤایەتی یا زانكۆیا زاخۆ
This study analyzes the role of purges as systemic mechanisms of governance within Stalin’s Soviet Union, Saddam Hussein’s Iraq, and Assad’s Syria. While commonly perceived as instruments for power consolidation, this paper argues that purges extend ...
Soran Tarkhani
doaj   +1 more source

“Nothing but a False Sense of Security”: Mapping and Critically Assessing Papal Support for a World Free from Nuclear Weapons

open access: yesJournal for Peace and Nuclear Disarmament, 2019
This article maps the papal peace witness’ support for a world free from nuclear weapons. Although the last concentration of scholarly work in this area dates back to the early and mid-1980s, now is a cogent time to update that scholarship by revisiting ...
Christopher Hrynkow
doaj   +1 more source

Preventing sexual violence in sport: Determinants of positive coach-bystander behavior

open access: yesFrontiers in Psychology, 2022
Given their central role and position, coaches are instrumental in creating safe sport environments, especially in preventing sexual violence, but little is known about bystander behaviors, hampering the development of effective bystander programs in the
Helena Verhelle   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

28. Community-Based Research: Learning About Attitudes Towards the Criminal Justice System

open access: yesCollected Essays on Learning and Teaching, 2012
Research points to the pedagogical value of an engaged and community service-learning approach to developing understanding of course content (Astin, Vogelgesang, Ikeda, & Yee, 2000).
Tammy A Marche, Jennifer Briere
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

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