Results 91 to 100 of about 585,728 (383)

LncRNA Foxo6os as a Novel “ Scaffold” Mediates MYBPC3 in Combating Pathological Cardiac Hypertrophy and Heart Failure

Advanced Science, EarlyView.
Schematic overview showing that forkhead box O6, opposite strand (Foxo6os) acts as a “scaffold”, directly binding myosin‐binding protein‐C (MYBPC3) and recruiting protein kinase C (PKC‐α) to mediate site‐specific phosphorylation of MYBPC3. This post‐translational modification supports cardiac contraction by regulating L‐type Ca2+ channels, especially ...
Jie Sheng, Qin Lin, Yizhuo Sun, Yilei Meng, Sangyu Hu, Huaming Cao, Fang Lin, Yuping Zhu, Luying Peng, Li Li   +9 more
wiley   +1 more source

Thoracoscopic repair of iatrogenic injury to thoracic aorta during minimally-invasive esophagectomy: A case report and literature review

Annals of Vascular Surgery - Brief Reports and Innovations, 2022
Introduction: Aortic injury is a devastating complication in any surgery, and although rare it can occur during intrathoracic dissection of the oesophagus. This case report describes the successful thoracoscopic management of an iatrogenic thoracic aorta
Jingting Wu, Jeremy TH Tan, Jack Kian Ch'ng   +2 more
doaj  

The Choice of Vascular Implants in Accordance with Age-Related Vessel Changes

Неотложная медицинская помощь, 2020
Background Today, one of the problems of modern society in the health are the high rates of mortality from cardiovascular disease.Aim of study Study of physico-mechanical properties of the vascular implants and aortic wall to support an adequate choice ...
V. A. Lipatov, N. N. Grigoryev, D. A. Severinov, A. R. Sahakyan   +3 more
doaj   +1 more source

Quantitative Analysis of Vortical Blood Flow in the Thoracic Aorta Using 4D Phase Contrast MRI

PLoS ONE, 2015
Introduction Phase contrast MRI allows for the examination of complex hemodynamics in the heart and adjacent great vessels. Vortex flow patterns seem to play an important role in certain vascular pathologies. We propose two- and three-dimensional metrics
J. von Spiczak, G. Crelier, D. Giese, S. Kozerke, D. Maintz, A. Bunck   +5 more
semanticscholar   +1 more source

Descending aortic calcification increases renal dysfunction and in-hospital mortality in cardiac surgery patients with intraaortic balloon pump counterpulsation placed perioperatively : a case control study [PDF]

, 2012
Introduction: Acute kidney injury (AKI) after cardiac surgery increases length of hospital stay and in-hospital mortality. A significant number of patients undergoing cardiac surgical procedures require perioperative intra-aortic balloon pump (IABP ...
Bingold, Tobias Michael, Eltzschig, Holger K., Lawlor, Garrett, Mitani, Aya, Nowak-Machen, Martina, Rawn, James D., Rosenberger, Peter, Shekar, Prem S., Shernan, Stanton K., Tuli, Sagun   +9 more
core   +2 more sources

FOXM1 Protects Against Myocardial Ischemia‐Reperfusion Injury in Rodent and Porcine Models by Suppressing MKRN1‐Dependent LKB1 Ubiquitination

Advanced Science, EarlyView.
FOXM1 maintains mitochondrial bioenergetic function by inhibiting MKRN1‐mediated ubiquitination of LKB1 in cardiomyocytes. Loss of FOXM1 in cardiomyocytes results in upregulation of MKRN1, which enhances LKB1 ubiquitination and disrupts AMPK signaling and energy metabolism pathways. Conversely, FOXM1 overexpression preserves mitochondrial bioenergetics
Shuai Song, Xiaokai Zhang, Zihang Huang, Zhiqiang Pei, Linqi Zeng, Fengze Cai, Tongyao Wang, Mohan Li, Chenyan Liu, Yining Song, Jiahao Guo, Hao Lu, Xinyu Weng, Li Shen, Xiaochun Zhang, Xingxing Cai, Aijun Sun, Junbo Ge   +17 more
wiley   +1 more source

Thoracic endovascular aortic repair for avulsion of aortic branches in a trauma patient requiring resuscitative thoracotomy: a case report

Surgical Case Reports, 2022
Background Resuscitative thoracotomy is a lifesaving procedure for trauma patients that are hemodynamically unstable. Cross-clamping of the descending thoracic aorta is an essential procedure performed during resuscitative thoracotomy in patients with ...
Atsushi Tanikawa, Takeaki Sato, Motoo Fujita, Chieri Tsuchiya, Ken Katsuta, Yusuke Suzuki, Kiichiro Kumagai, Yoshikatsu Saiki, Shigeki Kushimoto   +8 more
doaj   +1 more source

Analysis of the molecular mobility of collagen and elastin in safe, atheromatous and aneurysmal aortas [PDF]

, 2012
Aim of the study : In this study, we propose to use a thermal technique, Differential Scanning Calorimetry (DSC) to follow the evolution of elastin and collagen in safe and pathological cardiovascular tissues.
Dandurand, Jany, Degani, Annamaria, Gandaglia, Alessandro, Gargiulo, Mauro, Lacabanne, Colette, Samouillan, Valérie, Spina, Michel, Stella, Andréa   +7 more
core   +2 more sources

Salvage esophagectomy for unresectable locally advanced esophageal squamous cell carcinoma: Significant or not?

Annals of Gastroenterological Surgery, EarlyView.
Abstract We reviewed the current status and perspectives on salvage esophagectomy for initially unresectable locally advanced esophageal squamous cell carcinoma (ESCC) in the era of minimally invasive surgery and immunotherapy. Although the standard treatment for these patients is definitive chemoradiotherapy (CRT), the complete response rate to CRT ...
Hiroshi Saeki, Makoto Sakai, Takayoshi Watanabe, Makoto Sohda, Ken Shirabe   +4 more
wiley   +1 more source

Selectivity of Ca2+ channel blockers for dilator actions on the isolated lower esophageal sphincter and aorta from rats

Journal of Pharmacological Sciences, 2018
We compared dilator actions of representative four Ca2+ channel blockers on the isolated lower esophagus sphincter (LES) and thoracic aorta from rats.
Akira Takahara, Shuhei Nozaki, Akane Ishiguro, Kaori Okamura, Xin Cao, Megumi Aimoto, Yoshinobu Nagasawa   +6 more
doaj