Results 161 to 170 of about 429,555 (253)

An Experimental Measurement Method to Characterize and Apply Platinum Silicon Material for a Biomechanical Replica of the Thoracic Aorta. [PDF]

Biomimetics (Basel)
Grave-Capistrán MA, Lamonaca F, Carbone G, Torres-SanMiguel CR.   +3 more
europepmc   +1 more source

Targeted delivery of the CB2 receptor agonist JWH‐133 via VCAM‐1‐functionalised nanoparticles attenuates atherosclerosis and reveals sex‐specific therapeutic outcomes

British Journal of Pharmacology, EarlyView.
Background and Purpose Atherosclerosis, a chronic inflammatory disease characterised by lipid accumulation and endothelial dysfunction, remains a leading cause of cardiovascular morbidity and mortality. While cannabinoid 2 (CB2) receptor agonists show therapeutic promise in preclinical studies, their systemic application is hindered by poor ...
Lucía Martín‐Navarro, Lucía Martín‐Banderas, Josefa Álvarez‐Fuentes, María Dolores Herrera‐González   +3 more
wiley   +1 more source

Iatrogenic perforation of a branch of the descending thoracic aorta during catheter ablation of the left lateral accessory pathway: a case report. [PDF]

Int J Surg Case Rep
Yaminisharif A, Hajizeinali A, Hali R, Shirani S, Shahi S, Ebrahimi N.   +5 more
europepmc   +1 more source

Kininase I drives angiotensin II‐induced hypertension through activation of the bradykinin B1 receptor

British Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Kininase I, comprising carboxypeptidase N (CPN) and carboxypeptidase M, regulates kinin activity and is up‐regulated during injury, inflammation and immune activation. Under these conditions, kininase I converts bradykinin and kallidin into des‐Arg kinins, primary endogenous agonists of the bradykinin B1 receptor (R ...
Acacia White, Drew Theobald, Alexandra Johnston, David A. Tulis, Johanna Hannan, Srinivas Sriramula   +5 more
wiley   +1 more source

Mitochondrial dysfunction drives age-related degeneration of the thoracic aorta. [PDF]

Geroscience
Dhanekula AS, Harrison BR, Pharaoh G, Mattson-Hughes A, Tarantini S, Stuppard R, DeRoo SC, Burke CR, Hwang B, Pal JD, Mulligan MS, Marcinek DJ.   +11 more
europepmc   +1 more source

MD‐1 Deficiency Mitigates Atherosclerosis by Inhibiting NLRP3 Inflammasome Activation via cGAS‐STING Dependent Pathway in Macrophages

Cell Proliferation, EarlyView.
MD‐1 is induced and activated in macrophages. The activated MD‐1 subsequently promotes the cGAS‐STING‐TBK1‐IRF3 signalling pathway to activate the NLRP3 inflammasome, and subsequently increases pro‐inflammatory macrophage polarisation and decreases plaque stability to accelerate the development of atherosclerosis.
Fang Zhao, Zhili Jin, Zhiwei Cai, Quan Zhang, Tao He, Xiangjie Kong, Ming Chen, Zhibing Lu, Xiaorong Hu, Wen‐Lin Cheng   +9 more
wiley   +1 more source

Geometric Aging of the Thoracic Aorta: Insights From 2 Large Cohorts. [PDF]

Hypertension
Beeche CA, Tavolinejad H, Zhao B, Segers P, Duda JT, Gee J, Witschey WR, Penn Medicine Biobank*, Chirinos JA.   +8 more
europepmc   +1 more source

Academic Achievement Test for Anatomy of the Neck: Validity and Reliability Analysis

European Journal of Dental Education, EarlyView.
ABSTRACT Objective Anatomy education remains a fundamental component of medical and dental curricula, and mastering neck anatomy is particularly challenging due to its structural complexity and clinical relevance. Despite its importance, there is a limited number of validated instruments specifically designed to assess academic achievement in neck ...
Dilber Polat, Halil Yilmaz
wiley   +1 more source

RLIM‐associated neurodevelopmental disorders: From clinical spectrum to molecular mechanisms

The FEBS Journal, EarlyView.
RLIM (RNF12) is an E3 ubiquitin ligase essential for mammalian development. Loss‐of‐function variants cause Tønne–Kalscheuer syndrome, while duplications cause Xq13 duplication syndrome, highlighting RLIM dosage sensitivity. This review summarizes the genetics, clinical features, and molecular mechanisms of RLIM‐associated disorders, integrating ...
Madison Landon, Kyra Swildens, Vera M. Kalscheuer, Cristina Gontan, Francisco Bustos   +4 more
wiley   +1 more source

Endovascular repair of diseases originating in the ascending thoracic aorta: A systematic review and meta-analysis. [PDF]

JTCVS Struct Endovasc
de Kort JF, Been M, Hasami NA, Grassi V, Piffaretti G, Gelpi G, de Bruin JL, Hazenberg CEVB, Twine CP, Heijmen R, Wanhainen A, van Herwaarden JA, Trimarchi S.   +12 more
europepmc   +1 more source