Patient-specific predictions of aneurysm growth and remodeling in the ascending thoracic aorta using the homogenized constrained mixture model [PDF]
Biomechanics and Modeling in Mechanobiology, Springer Verlag,
2019, 18 (6), pp.1895-1913, 2019 In its permanent quest of mechanobiological homeostasis, our vascula-ture significantly adapts across multiple length and time scales in various physiological and pathological conditions. Computational modeling of vascular growth and remodeling (G\&R) has significantly improved our insights of the mechanobio-logical processes of diseases such as ...
arxiv +1 more source
Characterization of chemoelastic effects in arteries using digital volume correlation and optical coherence tomography [PDF]
, 2019 Understanding stress-strain relationships in arteries is important for fundamental investigations in mechanobiology. Here we demonstrate the essential role of chemoelasticity in determining the mechanical properties of arterial tissues. Stepwise stress-relaxation uniaxial tensile tests were carried out on samples of porcine thoracic aortas immersed in ...
arxiv +1 more source
Deep Learning-based Automated Aortic Area and Distensibility Assessment: The Multi-Ethnic Study of Atherosclerosis (MESA) [PDF]
arXiv, 2021 This study applies convolutional neural network (CNN)-based automatic segmentation and distensibility measurement of the ascending and descending aorta from 2D phase-contrast cine magnetic resonance imaging (PC-cine MRI) within the large MESA cohort with subsequent assessment on an external cohort of thoracic aortic aneurysm (TAA) patients.
arxiv
Aneurism of the Thoracic Aorta [PDF]
The Boston Medical and Surgical Journal, 1878 n ...
openaire +2 more sources
Computational hemodynamics in arteries with the one-dimensional augmented fluid-structure interaction system: viscoelastic parameters estimation and comparison with in-vivo data [PDF]
J. Biomech. 100 (2020) 109595, 2019 Mathematical models are widely recognized as a valuable tool for cardiovascular diagnosis and the study of circulatory diseases, especially to obtain data that require otherwise invasive measurements. To correctly simulate body hemodynamics, the viscoelastic properties of vessel walls are a key aspect to be taken into account as they play an essential ...
arxiv +1 more source
Neural operator learning of heterogeneous mechanobiological insults contributing to aortic aneurysms [PDF]
arXiv, 2022 Thoracic aortic aneurysm (TAA) is a localized dilatation of the aorta resulting from compromised wall composition, structure, and function, which can lead to life-threatening dissection or rupture. Several genetic mutations and predisposing factors that contribute to TAA have been studied in mouse models to characterize specific changes in aortic ...
arxiv
Data-driven generation of 4D velocity profiles in the aneurysmal ascending aorta [PDF]
arXiv, 2022 Numerical simulations of blood flow are a valuable tool to investigate the pathophysiology of ascending thoracic aortic aneurysms (ATAA). To accurately reproduce hemodynamics, computational fluid dynamics (CFD) models must employ realistic inflow boundary conditions (BCs).
arxiv
Interrupted Thoracic Aorta in an Octogenarian
Journal of the American College of Cardiology, 2014 ![Figure][1] [![Graphic][3] ][3][![Graphic][4] ][4] An 81-year-old man with rheumatic heart disease and hypertension presented with dyspnea on exertion. His chest roentgenogram is shown (A) . Transthoracic echocardiography showed severe aortic and mitral stenosis.
Hari P. Chaliki +3 more
openaire +3 more sources
A novel formulation for the study of the ascending aortic fluid dynamics with in vivo data [PDF]
arXiv, 2022 Numerical simulations to evaluate thoracic aortic hemodynamics include a computational fluid dynamic (CFD) approach or fluid-structure interaction (FSI) approach. While CFD neglects the arterial deformation along the cardiac cycle by applying a rigid wall simplification, on the other side the FSI simulation requires a lot of assumptions for the ...
arxiv
Aortic and arterial mechanics [PDF]
Cardiovascular Mechanics, 2018, 2019 Knowledge of the mechanical properties of the aorta is essential as important concerns regarding the treatment of aortic pathologies, such as atherosclerosis, aneurysms and dissections, are fundamentally mechanobiological. A comprehensive review is presented in the current chapter. As the function of arteries is to carry blood to the peripheral organs,
arxiv