Results 71 to 80 of about 585,728 (383)

Multimodal Investigation of Angiogenesis and Its Prevention by Small Compounds in a Zebrafish Cancer Model

Advanced Science, EarlyView.
A combined optical coherence tomography angiography and fluorescence imaging approach assesses tumor angiogenesis and drug effects in a novel zebrafish cancer model. By analyzing 3D vasculature data, the two imaging methods complement each other to quantify blood flow, vessel structure, and drug efficacy.
Marco Andreana, Ryan Sentosa, Caterina Sturtzel, Martin Pfister, René Werkmeister, Anna Schmitt, David Traver, Rainer Leitgeb, Wolfgang Drexler, Martin Distel, Angelika Unterhuber   +10 more
wiley   +1 more source

Proximal aortic stiffening in Turner patients may be present before dilation can be detected : a segmental functional MRI study [PDF]

, 2017
Background: To study segmental structural and functional aortic properties in Turner syndrome (TS) patients. Aortic abnormalities contribute to increased morbidity and mortality of women with Turner syndrome.
Achten, Eric, Babin, Danilo, De Groote, Katya, De Schepper, Jean, Demulier, Laurent, Devos, Daniel, Rietzschel, Ernst, Segers, Patrick, Taeymans, Yvo, Van Bortel, Lucas, Westenberg, Jos J   +10 more
core   +2 more sources

The GRK2/AP‐1 Signaling Axis Mediates Vascular Endothelial Dysfunction and Atherosclerosis Induced by Oscillatory Low Shear Stress

Advanced Science, EarlyView.
This study highlights GRK2 is a central mediator in OSS‐induced endothelial dysfunction. OSS activates GPCRs in endothelial cells, leading to GRK2 phosphorylation and the activation of AP‐1. AP‐1 induces inflammation, while also promoting NR4A1 expression and anchoring LKB1 in the nucleus, which suppresses AMPK activity. This cascade causes endothelial
Li‐Da Wu, Yi Shi, Chao‐Hua Kong, Ai‐Qun Chen, Ying Kang, Jun‐Yan Kan, Xiao‐Min Jiang, Peng Chu, Dong‐Chen Wang, Yi‐Fei Lv, Zhi‐Yuan Qian, Zi‐Hao Jiang, Yun‐Wei Chen, Yue Sun, Rui‐Rui Chang, Wen‐Ying Zhou, Yue Gu, Jun‐Xia Zhang, Shao‐Liang Chen   +18 more
wiley   +1 more source

Fatores de risco na cirurgia das dissecções da aorta ascendente e arco aórtico Risk factors in surgery for thoracic aortic dissection

Brazilian Journal of Cardiovascular Surgery, 1987
A experiência cirúrgica no tratamento de 72 pacientes consecutivos com dissecções da aorta proximal foi analisada, com o objetivo de identificar os fatores agravantes do risco da operação.
Luiz Felipe P Moreira, Noedir A. G Stolf, Caio B Vianna, Paulo M Pêgo-Fernandes, Antônio C. Pereira Barreto, Geraldo Verginelli, Adib D Jatene   +6 more
doaj  

Remodeling of Aortic Configuration and Abdominal Aortic Branch Perfusion After Endovascular Repair of Acute Type B Aortic Dissection: A Computed Tomographic Angiography Follow-Up

Frontiers in Cardiovascular Medicine, 2021
Background: Thoracic endovascular aortic repair (TEVAR) for type B aortic dissection (TBAD) induces false lumen (FL) thrombosis, promotes favorable aortic remodeling, and makes an impact on abdominal aortic branch perfusion patterns.
Zihui Yuan, Yiqing Li, Bi Jin, Jian Wang
doaj   +1 more source

Contribution of collagen fiber undulation to regional biomechanical properties along porcine thoracic aorta.

Journal of Biomechanical Engineering, 2015
As major extracellular matrix components, elastin, and collagen play crucial roles in regulating the mechanical properties of the aortic wall and, thus, the normal cardiovascular function.
Shahrokh Zeinali-Davarani, Yunjie Wang, Ming-Jay Chow, Raphaël Turcotte, Yanhang Zhang   +4 more
semanticscholar   +1 more source

Risk Factors for Thoracic Aortic Dissection

Genes, 2022
Thoracic aortic aneurysms involving the root and/or the ascending aorta enlarge over time until an acute tear in the intimal layer leads to a highly fatal condition, an acute aortic dissection (AAD).
Zhengchun Zhou, A. Cecchi, Siddharth K. Prakash, D. Milewicz   +3 more
semanticscholar   +1 more source

Association of Cystic Medial Necrosis of the Aorta and Undiagnosed Thyroiditis [Scripta Medica] [PDF]

, 1977
We have recently seen two patients with cystic medial necrosis of the aorta. The first patient died of a dissecting aneurysm of the thoracic aorta. At autopsy, classical Hashimoto’s thyroiditis was discovered.
Hain, John R., Wise, William S.
core   +1 more source

Leptin Aggravates Thoracic Aortic Dissection Through Impairment of Energy Metabolism in Nrip2+ Smooth Muscle Cells

Advanced Science, EarlyView.
Epidemiological data confirm obesity elevates thoracic aortic dissection (TAD) risk. Patient analyses implicate hyperleptinemia, where leptin binding to vascular smooth muscle cell (VSMC) receptors triggers Socs3‐mediated suppression of Stat5a transcriptional activity.
Ling Chen, Yujie Zhu, Xi Yang, JiangBin Wu, Keyuan Chen, Wuqing Huang, Lu Fang, Qi Zhang, Jie Chen, Jianing Gao, Huanhuan Cao, Meifang Wu, Zhihuang Qiu, Yuling Zhang, Yue Shen, Qiuyu Huang, Zhiyong Lin, Lemin Zheng, Liangwan Chen   +18 more
wiley   +1 more source

The Evolution of Aortic Aneurysm Repair: Past Lessons and Future Directions [PDF]

, 2011
The history and evolution of aortic aneurysm repair demonstrates an important paradigm within surgery, namely the importance of surgical pioneers and innovators who have\ud strived to achieve technical excellence and improve patient care.
Bhogal, Ricky Harminder, Downing, Richard   +1 more
core   +1 more source