Results 41 to 50 of about 33,658 (179)

Single‐Cell Profiling Identifies CLEC5A+ Macrophages as Key Drivers of Thoracic Aortic Aneurysm Via CCL5‐Mediated M1 Polarization

Journal of Clinical Laboratory Analysis, EarlyView.
Thoracic aortic aneurysm (TAA) is a life‐threatening cardiovascular disease with limited therapeutic options. Through single‐cell RNA sequencing of aortic tissues from healthy individuals and TAA patients (105,541 cells), we identified CLEC5A+macrophages as the predominant pathogenic cell population exhibiting the highest M1 polarization score. Machine
Xiangyu Li, Chunguang Guo, Mingyao Luo, Chang Shu   +3 more
wiley   +1 more source

The polymorphisms in angiotensin-converting enzyme and angiotensin-converting enzyme 2 are not associated with thoracic aortic diseases and coronary heart disease

Proceedings of Singapore Healthcare, 2016
Introduction: The polymorphisms of the angiotensin-converting enzyme (ACE) and angiotensin-converting enzyme 2 (ACE2) genes have been demonstrated to be involved in some cardiovascular diseases.
Yang Li, Er Yong Zhang, Zhong Wu
doaj   +1 more source

Gene knockdown of angiopoietin-like protein 3 reduces the occurrence and development of thoracic aortic aneurysms [PDF]

Jichu yixue yu linchuang, 2021
Objective To explore the role of angiopoietin-like protein 3 (ANGPTL3) in the development of thoracic aortic aneurysm (TAA) and its possible mechanism. Methods The TAA patients who underwent open surgical repair in Beijing Anzhen Hospital were selected
YU Hua-hui, JIAO Xiao-lu, YANG Yun-yun, LI Fan, SUN Qiu-ju, YU Yu, LYU Qian-wen, QIN Yan-wen
doaj  

Sonographic Diagnosis of an Intercostal Artery Pseudoaneurysm: A Case Report and Literature Review

Journal of Clinical Ultrasound, EarlyView.
A 63‐year‐old male presented to the emergency department after being found unconscious during a welfare check. Following a prolonged three‐month hospital admission, the patient developed left flank pain. Spectral Doppler ultrasound revealed a large isoechoic lesion with layering echoes, and spectral Doppler demonstrated bidirectional flow.
Aaditya P. Singh, Peter R. Coombs
wiley   +1 more source

Existing and Emerging Approaches to Risk Assessment in Patients with Ascending Thoracic Aortic Dilatation

Journal of Imaging, 2022
Ascending thoracic aortic aneurysm is a life-threatening disease, which is difficult to detect prior to the occurrence of a catastrophe. Epidemiology patterns of ascending thoracic aortic dilations/aneurysms remain understudied, whereas the risk ...
Nina D. Anfinogenova, Valentin E. Sinitsyn, Boris N. Kozlov, Dmitry S. Panfilov, Sergey V. Popov, Alexander V. Vrublevsky, Alexander Chernyavsky, Tatyana Bergen, Valery V. Khovrin, Wladimir Yu. Ussov   +9 more
doaj   +1 more source

Parallel Graft Technique in a Complex Aortic Aneurysm: The Value of Intra-operative Flexibility from The Original Operative Plan

EJVES Short Reports, 2019
Introduction: The parallel grafting technique (PGT) is a valuable alternative to prefabricated branched or fenestrated endovascular aortic repair. An often overlooked advantage of PGT is its unique adaptability to different anatomical challenges that ...
Ricardo Castro-Ferreira, Paulo G. Dias, Sérgio M. Sampaio, José F. Teixeira, Armando C. Lobato   +4 more
doaj   +1 more source

Awake Blue Laser Excision and Balloon Dilation of Oropharyngeal Stenosis in High‐Risk Patients

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Oropharyngeal stenosis is a rare condition that can develop following head and neck cancer treatment, leading to progressive dyspnea, dysphagia, and dysphonia. Patients with symptomatic dyspnea may benefit from endoscopic surgery. However, head and neck cancer survivors can have severe trismus, limited neck extension, and altered laryngeal ...
Abbey L. Landini, Cyrus W. Abrahamson, Andrew P. Stein   +2 more
wiley   +1 more source

Cardiovascular complications of tertiary syphilis: rupture of the aneurysm of the descending thoracic aorta, followed by the formation of an aortoesophageal fistula

Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье
Relevance. 30% patients who infected syphilis during the long time have got complications characterized as tertiary syphilis. Vascular complications often manifest after 15–30 years.
N. R. Chernaya, V. V. Loseva, N. S. Gorshkov, V. S. Selyaev, E. B. Nikolaeva, L. S. Kokov   +5 more
doaj   +1 more source

Chronic Thoracic Aortic Aneurysm Presenting 29 Years following Trauma

Case Reports in Surgery, 2015
Blunt, nonpenetrating injuries of the thoracic aorta are uncommon and associated with a high mortality rate within the first hour. Aortic injury is missed in 1-2% of patients that survive to hospital, and a chronic thoracic aortic aneurysm may ...
Sarah Miller, Prashant Kumar, Rene Van den Bosch, Adib Khanafer   +3 more
doaj   +1 more source

Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases

Cell Proliferation, EarlyView.
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du, Joshua S. Fleishman, Shuang Wu, Yuan Zhou, Clara X. Wang, Haitong Wang, Yumin Wang, Hongquan Wang   +7 more
wiley   +1 more source