Reactive oxygen species in thoracic aortic dissection: Insights into mechanisms and disease progression. [PDF]
Jiang M +5 more
europepmc +1 more source
Tomo-seq identifies NINJ1 as a potential target for anti-inflammatory strategy in thoracic aortic dissection. [PDF]
Sheng Y +15 more
europepmc +1 more source
Slit2/Robo Signaling Restores Diabetic Erectile Function via Neurovascular Remodeling
ABSTRACT Background Diabetes mellitus‐induced erectile dysfunction (DMED) is a common and debilitating vascular‐neurogenic complication of diabetes. The poor responsiveness of DMED patients to phosphodiesterase type‐5 inhibitors underscores the need for therapies capable of restoring both endothelial integrity and cavernous nerve function.
Sen Fu +7 more
wiley +1 more source
Targeting Endothelial PDK4-EndoMT Feedback Loop Mitigates the Development of Thoracic Aortic Dissection in Mice. [PDF]
Cao X +13 more
europepmc +1 more source
KIF6 Trp719Arg Genetic Variant Increases Risk for Thoracic Aortic Dissection. [PDF]
Velasco JJ +8 more
europepmc +1 more source
This is the first study assessing in vivo blood flow profiles during extracorporeal circulation (ECC) scenarios. Magnetic resonance imaging data served for the calibration of computational fluid dynamics algorithms, enabling accurate replication of the hemodynamic conditions.
Anna Kathrin Assmann +9 more
wiley +1 more source
Automated AI detection of thoracic aortic dissection on CT imaging. [PDF]
Norajitra T +11 more
europepmc +1 more source
Low Zinc Alleviates the Progression of Thoracic Aortic Dissection by Inhibiting Inflammation. [PDF]
Zhu L +6 more
europepmc +1 more source
Targeting m6A Modifications Regulating Ferroptosis Offers Novel Therapy in Diseases
m6A RNA modification regulates ferroptosis by balancing iron metabolism, lipid peroxidation, and antioxidant defenses. Dysregulated m6A signaling disrupts pro‐ and anti‐ferroptotic factors, leading to excess ROS, Fe3+ accumulation, and lipid peroxidation–driven cell death. Targeting m6A‐mediated ferroptotic regulation represents a promising therapeutic
Lida Du +7 more
wiley +1 more source
A 4-Decade Population-Based Registry of Thoracic Aortic Dissection Causing Sudden Death in the Young. [PDF]
De Gaspari M +14 more
europepmc +1 more source

