Results 121 to 130 of about 2,652,693 (300)

AI Designed Conformation Locking Peptides Target STING to Restore Diabetic Wound Healing

Advanced Science, EarlyView.
A generative AI pipeline identifies SCP‐1, a conformation‐locking peptide that stabilizes inactive STING. Incorporated into a dual‐responsive hydrogel for localized, MMP‐9‐triggered release, SCP‐1 suppresses inflammation, promotes reparative macrophage polarization, and accelerates diabetic wound healing.
Xinyu Li, Haojie Fu, Zhe Wang, Xuanzhou Chen, Ruhong Zhang, Xudong Wang, Louis D. Zhang, Xiang Li, Datao Li   +8 more
wiley   +1 more source

Extent of Lung Resection in Non-small Lung Cancer with Interlobar Lymph Node Involvement

, 2011
Background: Optimal resection type for non-small cell lung cancer (NSCLC) with interlobar lymph node involvement (ILNI) has seldom been reported.
Atilla Gurses, Akif Turna, Ibrahim, Seyyit, Gunluoglu, Mehmet Zeki, Mehmet Zeki Gunluoglu, Adalet Demir, Deniz Sansar, Melek, Huseyin, Huseyin Melek, Gurses, Atilla, Turna, Akif, Demir, Adalet, Sansar, Deniz, Seyyit Ibrahim Dincer   +13 more
core   +1 more source

Endothelial YAP Signaling Promotes Blood‐Spinal Cord Barrier Repair in Mice After Spinal Cord Injury

Advanced Science, EarlyView.
Endothelial YAP is required for blood‐spinal cord barrier repair after spinal cord injury. YAP‐dependent vascular repair is associated with ANGPT1/PI3K/AKT signaling in vivo and may involve endothelial‐pericyte paracrine interactions. By supporting vascular remodeling, tight junction restoration, restored pericyte coverage, and astrocyte‐vascular ...
Jiawei Wang, Yaozhi He, Yanjiao Wang, Jingjing Zhang, Qishun Liang, Mengxian Jia, Yumin Wu, Zongjie Yuan, Ziwei Fan, Yuxuan Li, Huihui Zhang, Qinjiao Fu, Ying Wang, Zhihui Huang, Honglin Teng   +14 more
wiley   +1 more source

Value of peripheral blood circulating tumor cell detection in the diagnosis of thoracic diseases and the prediction of severity. [PDF]

Clin Exp Med, 2023
Qi C, Xiong XZ.
europepmc   +1 more source

Fibrillarin Resists Cellular Senescence Via SIRT1‐Dependent Nicotinamide Metabolism and Its Inhibition Sensitizes Senolytic Therapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
FBL directly binds to and stabilizes SIRT1 by blocking its ubiquitin‐proteasome degradation, thereby sustaining nicotinamide metabolism and redox homeostasis to counteract cellular senescence in ESCC. Genetic and pharmacological suppression of FBL sensitizes tumor cells to senolytic therapy.
Xing Jin, Hong Liu, Ling Gao, Lei Liu, Ji‐Bin Liu, Xiaoxia Jin, Ming‐Song Wang, Dan Liu, Li Feng, Wen‐Lian Chen   +9 more
wiley   +1 more source

PediCXR: An open, large-scale chest radiograph dataset for interpretation of common thoracic diseases in children. [PDF]

Sci Data, 2023
Pham HH, Nguyen NH, Tran TT, Nguyen TNM, Nguyen HQ.   +4 more
europepmc   +1 more source

An innovative numerical approach to resolve the pulse wave velocity in a healthy thoracic aorta model

, 2017
Aortic dissection and atherosclerosis are highly fatal diseases. The development of both diseases is closely associated with highly complex haemodynamics.
Yang, An-Shik;Wen, Chih-Yung;Tseng, Li-Yu;Chiang, Chih-Chieh;Tseng, Wen-Yih Isaac;Yu, Hsi-Yu, 虞希禹   +1 more
core   +1 more source

Senkyunolide I Inhibits mtDNA‐cGAS‐STING Signaling in Macrophages via Targeting VDAC1 Oligomerization to Attenuate Ulcerative Colitis

Advanced Science, EarlyView.
In macrophages, senkyunolide I (SEI) directly targets the K12 residue of VDAC1 to inhibit its stress‐induced oligomerization, a critical upstream event that effectively prevents mitochondrial DNA release and subsequent cGAS‐STING pathway activation.
Zhiming Ye, Yihang Huang, Bohao Han, Lei Zhang, Can Yu, Yang Yang, Bing Liu, Yongping Jian, Zhixiang Xu, Cheng Zeng   +9 more
wiley   +1 more source

THORACIC SURGERY. THE SURGICAL TREATMENT OF THORACIC DISEASE

Southern Medical Journal, 1926
Mode of access: Internet.
openaire   +3 more sources

Controlled Hypothermic Storage for Lung Preservation: Leaving the Ice Age Behind

Transplant International
Controlled hypothermic storage (CHS) is a recent advance in lung transplantation (LTx) allowing preservation at temperatures higher than those achieved with traditional ice storage.
Ismail Cenik, Ismail Cenik, Jan Van Slambrouck, Jan Van Slambrouck, An-Lies Provoost, An-Lies Provoost, Annalisa Barbarossa, Annalisa Barbarossa, Cedric Vanluyten, Cedric Vanluyten, Caroline Boelhouwer, Caroline Boelhouwer, Bart M. Vanaudenaerde, Robin Vos, Robin Vos, Jacques Pirenne, Jacques Pirenne, Dirk E. Van Raemdonck, Dirk E. Van Raemdonck, Laurens J. Ceulemans, Laurens J. Ceulemans   +20 more
doaj   +1 more source