Results 141 to 150 of about 473,507 (301)

Safety outcomes of antidiabetic medications: A comprehensive review of the EU summaries of product characteristics and international clinical practice guidelines

British Journal of Clinical Pharmacology, EarlyView.
Aims Information on the safety profile of antidiabetic medications is essential for informed treatment decisions in type 2 diabetes mellitus. Although this information is available in regulatory documents of individual drugs, a comprehensive overview across all approved antidiabetics is lacking.
David Liang, Daniala L. Weir, Safana Thevasahayam, Vera H. M. Deneer, Arno Siebes, Helga Gardarsdottir   +5 more
wiley   +1 more source

Left Main Bronchus Root Prolongation to Cure 3 Patients whose Carina is Involved by Lung Cancer

Chinese Journal of Lung Cancer, 2011
Background and objective Patient whose carina is involved by carcinoma is difficult to treat by surgery. The aim of this study is to evaluate the safety and effectiveness of left main bronchus root prolongation to cure these patients.
Yangkai LI, Chengcheng XU, Wei SUN, Ni ZHANG, Xiangning FU   +4 more
doaj  

SMARCA4‐Deficient Undifferentiated Thoracic Tumor: Clinical Features and Prognosis of a Case Series and Literature Review

The Clinical Respiratory Journal
Introduction Thoracic SMARCA4‐deficient undifferentiated tumors (SMARCA4‐UT) are rare and aggressive epithelioid neoplasms characterized by the loss of the SMARCA4 gene.
Fangzhen Shan, Shuntao Liang, Youwen Zhang, Wei Wu, Guangxia Yang, Mei Yan, Xuemei Zhang, Yumao Miao, Linlin Liu, Jingjing Cai, Zhitao Shi, Bangdong Liu, Nannan Zhang   +12 more
doaj   +1 more source

Tackling cancer stemness with nanotechnology in the era of precision medicine

BMEMat, EarlyView.
Precise customization of nanoparticles (NPs) enables active targeting of cancer stem cells (CSCs), thereby improving drug delivery and therapeutic efficacy. NP‐based probing enhances CSC detection through imaging and liquid biopsy, whereas diverse therapeutic payloads improve therapeutic outcomes.
Shaolei Guo, Shun Yao, Lihui Meng, Chunyuan Chen, Yuechu Lucinda Lu, Rong Lu, Kashif Rafiq Zahid, Umar Raza, Qingzhi Wu, Wenli Chen   +9 more
wiley   +1 more source

First‐Line Osimertinib in Patients with EGFR‐Mutant Advanced Non‐Small Cell Lung Cancer: Outcome and Safety in the Real World: FLOWER Study

The Oncologist, EarlyView., 2021
Abstract Lessons Learned Osimertinib has confirmed effectiveness in this real‐world population of patients with EGFR‐mutant advanced non‐small cell lung cancer. Thromboembolic events occur more frequently than previously reported, suggesting a thrombotic diathesis that requires further investigation. Patients with at least three metastatic sites, brain
Martina Lorenzi, Alessandra Ferro, Fabiana Cecere, Daniela Scattolin, Alessandro Del Conte, Alessandro Follador, Sara Pilotto, Valentina Polo, Mariacarmela Santarpia, Rita Chiari, Alberto Pavan, Alessandro Dal Maso, Valentina Da Ros, Giada Targato, Sabrina Vari, Stefano Indraccolo, Fiorella Calabrese, Stefano Frega, Laura Bonanno, Pier Franco Conte, Valentina Guarneri, Giulia Pasello   +21 more
wiley   +1 more source

Innovation of plant‐derived extracellular vesicles and interdisciplinary research: From discovery to biomedical applications

BMEMat, EarlyView.
Plant‐derived extracellular vesicles offer numerous advantages and are regarded as highly promising candidates in the field of biomedicine. Abstract Extracellular vesicles (EVs) are double‐membrane vesicular structures that can be secreted by nearly all living cells.
Zilin Li, Yi Wei, Ben Hu, Yafang Song, Xiaojia Chen, Nik Ahmad Nizam Nik Malek, Tongkai Chen   +6 more
wiley   +1 more source

Surgical Expert Consensus on Clinical Management of Advanced Thymoma and Thymic Carcinoma: A Beijing–Tianjin–Hebei Collaborative Initiative

Thoracic Cancer
Thymomas and thymic carcinomas represent rare epithelial‐derived thoracic neoplasms that, despite their low incidence, pose significant clinical challenges and impact patient survival.
Zhen Yu, Peng Zhang, Guoyan Qi, Deruo Liu, Tao Yu, YunFeng Zhang, Ji Ke, Xingguo Yang, Baoxun Zhang, Xintao Yu, Jian Cui, Xiang Gao, Lei Yu   +12 more
doaj   +1 more source

Early Experience With Evoque Transcatheter Tricuspid Valve Replacement in Carcinoid Heart Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Tricuspid regurgitation (TR) is nearly universal in carcinoid heart disease (CHD), but surgical replacement carries significant risk, and CHD was excluded from the landmark TRISCEND II trial. We present seven patients with CHD undergoing Evoque transcatheter tricuspid valve replacement (TTVR) at two tertiary centers.
Jackson S. Burton, Ben Peterson, Brian Whisenant, Anwar Tandar   +3 more
wiley   +1 more source

Minimally invasive surgery versus open surgery for the treatment of solid abdominal and thoracic neoplasms in children. [PDF]

Cochrane Database Syst Rev, 2015
van Dalen EC, de Lijster MS, Leijssen LG, Michiels EM, Kremer LC, Caron HN, Aronson DC.   +6 more
europepmc   +1 more source

IMPORTANCE OF IMMUNOHISTOCHEMISTRY IN THE DIFFERENTIAL DIAGNOSIS OF THORACIC NEOPLASMS

Introduction: Thoracic neoplasms present a significant diagnostic challenge due to the anatomical complexity of the thorax and the morphological overlap between pulmonary, pleural, mediastinal, and metastatic tumors. Although imaging techniques allow for adequate localization of lesions, their ability to establish tumor type is limited. In this context,
Marcel Leonardo Quintero Contreras, Anna Isabella Rojas Atencia, José Alexander Rubiano Pedroza   +2 more
openaire   +1 more source