Results 161 to 170 of about 534,403 (302)

Mendelian Randomization Study in East Asian Populations Supports the Causal Relationship Between Blood Metabolites and COPD: Insights from Amino Acids, Phospholipids, Vitamin D, and Trace Elements

open access: yesInternational Journal of COPD
Shixiang Guo,1,* Zheng Li,1,* Mingfeng Wei,1,* Lefei Hu,1 Shuai Jiang,1 Fuzhi Yang,1 Zhengyao Yang,2 Xunxia Zhu,1 Xiaoyong Shen1 1Department of Thoracic Surgery, Affiliated Huadong Hospital, Fudan University, Shanghai, People’s ...
Guo S   +8 more
doaj  

Robot-Assisted Thoracic Surgery for Lung Cancer in Juntendo University -Safety and benefit. [PDF]

open access: yesJuntendo Med J
Fukui M   +8 more
europepmc   +1 more source

Animal models of chronic thromboembolic pulmonary hypertension

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Current animal models of CTEPH. Created using BioRender.com. Abstract Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare, yet life‐threatening disorder characterized by persistent pulmonary vascular obstruction and elevated pulmonary artery pressure, with progressive remodeling and subsequent right heart failure.
Yong‐Jian Zhu   +5 more
wiley   +1 more source

A novel mouse model simulating C5 palsy after cervical surgery

open access: yesAnimal Models and Experimental Medicine, EarlyView.
This study establishes a reliable mouse model of permanent C5 palsy (post‐laminectomy complication) via dorsal approach, selectively severing the C5 anterior nerve root while preserving the posterior root through partial C4 and C5 laminectomy. The model successfully replicates clinical C5P features—flaccid shoulder paralysis, electrophysiological ...
Chenpei Xu   +8 more
wiley   +1 more source

Safety and feasibility of bilateral lung transplantation with video-assisted thoracic surgery. [PDF]

open access: yesSurg Endosc
Park JH   +10 more
europepmc   +1 more source

A novel mouse model of endometriosis: Simulating the recurrent hemorrhagic microenvironment of clinical lesions

open access: yesAnimal Models and Experimental Medicine, EarlyView.
To address the limitations of existing models, this study innovatively established a mouse model of endometriosis (EMs) capable of mimicking cyclic bleeding. Our results confirmed that this model recapitulates the complete pathological progression from ectopic lesion establishment to systemic responses, exhibiting superior clinical relevance compared ...
Yu Zhuang   +7 more
wiley   +1 more source

Clinical Characteristics and Prognosis of Non-Small Cell Lung Cancer with Coexisting Pulmonary Tuberculosis: A Retrospective Matched-Cohort Study

open access: yesJournal of Inflammation Research
Jing Zheng,1,2,* Haoran Xie,3,* Guocan Yu,1,2 Likui Fang,1,2 Min Gao,1,2 Fangming Zhong,1,2 Bo Ye,3 Wenfeng Yu1,2 1Department of Tuberculosis, Hangzhou Red Cross Hospital, Hangzhou, Zhejiang, 310003, People’s Republic of China ...
Zheng J   +7 more
doaj  

NUAK2 Inhibition Enhances Macromolecular Drug Delivery in a 3D Fibrotic Model of the Pancreatic Tumor Microenvironment

open access: yesAdvanced NanoBiomed Research, EarlyView.
Using a 3D cell culture model of the fibrotic barrier in pancreatic cancer, this work shows that inhibiting NUAK2 kinase in pancreatic stellate cells enhances macromolecular drug delivery. Mechanistically, NUAK2 inhibition disrupted actin stress fiber assembly to downregulate collagen I expression, thus enhancing macromolecular permeability.
Misaki Nakamura   +14 more
wiley   +1 more source

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