Results 281 to 290 of about 3,196,328 (354)

Aortic Dissection With Pseudoaneurysm Formation Masquerading as Pulmonary Embolism After Transcatheter Aortic Valve Replacement

open access: yesCatheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Transcatheter aortic valve replacement (TAVR) is a commonly performed procedure for the treatment of severe aortic stenosis. While it is generally considered a low‐risk procedure, one of the rare potentially life‐threatening complications includes aortic dissection.
Heather Wang   +3 more
wiley   +1 more source

Tislelizumab: Structural Innovations and Expanding Clinical Horizons in Next‐Generation PD‐1 Immunotherapy

open access: yesChronic Diseases and Translational Medicine, EarlyView.
The interaction of tislelizumab with PD‐1/PD‐L1 in the tumor microenvironment. Tislelizumab targets PD‐1 on T cells, blocking its interaction with PD‐L1 on tumor cells. This action is facilitated by a modified F(ab) region that limits Fc‐γ receptor binding, thereby enhancing the antitumor immune response. ABSTRACT Tislelizumab is a next‐generation PD‐1
Thy T. Nguyen   +4 more
wiley   +1 more source

A Nationwide Survey to Investigate Burnout and Quality of Life Among Thoracic Surgery Residents in Italy. [PDF]

open access: yesHealthcare (Basel)
Mattioni G   +14 more
europepmc   +1 more source

Towards the Use of Metabolic Volatiles in Breath for Determining Drug Response: Gstachamine as an Unlabeled Substrate to Measure CYP3A4 Activity

open access: yesChemMedChem, EarlyView.
A potential substrate, gstachamine, was engineered for a future CYP3A4 assay. HepG2 cell clones overexpressing CYP3A4 were used to investigate both liquid and headspace phases after incubation. A specific N‐dealkylated metabolite and butanone were detected using LC‐MS and PTR‐ToF‐MS, respectively.
Valentina Stock   +8 more
wiley   +1 more source

Thoracic and cardiovascular surgeries in Japan during 2023 : Annual report by the Japanese Association for Thoracic Surgery. [PDF]

open access: yesGen Thorac Cardiovasc Surg
Committee for Scientific Affairs   +31 more
europepmc   +1 more source

Multivariate Trajectories of Weight and Mental Health and Their Prognostic Significance 6 Years After Obesity Surgery

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Obesity surgery (OS) results in substantial, albeit heterogeneous, long‐term improvements in weight and mental health, with unclear trajectories and their associations. This study examined multivariate trajectories of weight, psychopathology, and health‐related quality of life (HRQOL) after OS, and their prospective association with ...
Anja Hilbert   +11 more
wiley   +1 more source

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