Results 121 to 130 of about 754,621 (359)

MISP Suppresses Ferroptosis via MST1/2 Kinases to Facilitate YAP Activation in Non‐Small Cell Lung Cancer

Advanced Science, EarlyView.
This study explores the role of Mitotic Spindle Positioning (MISP) as a key inhibitor of ferroptosis in non‐small cell lung cancer (NSCLC). MISP upregulation in NSCLC tissues leads to ferroptosis resistance, promoting cell proliferation. Mechanistically, MISP suppresses Hippo signaling via MST1/2 kinases, activating YAP and enhancing SLC7A11 expression,
Fuquan Zhang, Bingtao Huang, Yiming Xu, Guohong Cao, Mingjing Shen, Changmin Liu, Judong Luo   +6 more
wiley   +1 more source

Aesthetic outcomes after surgical repair of pectus excavatum in females: Differences between patients and professional evaluators

Archives of Plastic Surgery, 2020
Background Pectus excavatum is less common in females than in males, and it often aggravates a coexistent breast asymmetry. We conducted a study comparing female patients’ versus medical professionals’ evaluation of pectus excavatum repair to assess ...
Tanja Wachter, Barbara Del Frari, Michael Edlinger, Evi Maria Morandi, Christina Mayerl, Ralph Verstappen, Emre Celep, Gabriel Djedovic, Johann Kinzl, Anton Herbert Schwabegger, Dolores Wolfram   +10 more
doaj   +1 more source

False-negative upper extremity ultrasound in the initial evaluation of patients with suspected subclavian vein thrombosis due to thoracic outlet syndrome (Paget-Schroetter syndrome) [PDF]

, 2020
OBJECTIVE: To assess the utilization and consequences of upper extremity Duplex ultrasound in the initial diagnostic evaluation of patients with suspected subclavian vein (SCV) thrombosis and venous thoracic outlet syndrome (VTOS).
Abuirqeba, Ahmmad A, Brownie, Evan R, Ohman, J Westley, Rubin, Brian G, Thompson, Robert W   +4 more
core   +1 more source

Minimally Invasive Mitral Valve Surgery III: Training and Robotic-Assisted Approaches. [PDF]

, 2016
Minimally invasive mitral valve operations are increasingly common in the United States, but robotic-assisted approaches have not been widely adopted for a variety of reasons.
Agnihotri, Arvind K, Ailawadi, Gorav, Barnhart, Glenn R, Fayers, Trevor M, Goldman, Scott M, Grossi, Eugene A, Guy, T Sloane, Hargrove, W Clark, Hummel, Brian W, Khan, Junaid H, Lehr, Eric J, Lewis, Clifton TP, Malaisrie, S Chris, Mehall, John R, Murphy, Douglas A, Rodriguez, Evelio, Ryan, William H, Salemi, Arash, Segurola, Romualdo J, Shemin, Richard J, Smith, J Michael, Smith, Robert L, Weldner, Paul W, Wolfe, J Alan   +23 more
core   +1 more source

ISG15 Enhances the Activity of γ‐Glutamate Cysteine Ligase to Suppress Apoptosis in High Fat Diet‐Promoted Hepatocellular Carcinoma

Advanced Science, EarlyView.
Hepatocellular carcinoma (HCC) cells under high‐fat environment constrain harmful reactive oxygen species (ROS) by enhancing glutathione synthesis though upregulating interferon stimulated gene 15 (ISG15). In this process, upregulated high mobility group A1 (HMGA1) enhances ISG15 transcription, upregulated ISG15 subsequently noncovalently binds with ...
Xinran Liu, Qiujin Ma, Zhao Jia, Yihao Zhou, Churong Zou, Yushuo Xiao, Yuchen Chen, Chuyao Ma, Liangliang Song, Jing Yang, Chen Wang, Huidie Xu, Hong Chen, Jiajian Shi, Junqiu Yue, Yu Sun, Desheng Hu, Robert B Petersen, Yangkai Li, Anlin Peng, Kun Huang, Ling Zheng   +21 more
wiley   +1 more source

“High Frequency/Small Tidal Volume Differential Lung Ventilation”: A Technique of Ventilating the Nondependent Lung of One Lung Ventilation for Robotically Assisted Thoracic Surgery

Case Reports in Anesthesiology, 2015
With the introduction of new techniques and advances in the thoracic surgery fields, challenges to the anesthesia techniques had became increasingly exponential.
Bassam M. Shoman, Hany O. Ragab, Ammar Mustafa, Rashid Mazhar   +3 more
doaj   +1 more source

Standardization of elective tracheostomies at the Central Institute of the Hospital das Clínicas in São Paulo during the COVID-19 pandemic

Revista do Colégio Brasileiro de Cirurgiões, 2020
The COVID-19 Pandemic has resulted in a high number of hospital admissions and some of those patients need ventilatory support in intensive care units. The viral pneumonia secondary to Sars-cov-2 infection may lead to acute respiratory distress syndrome (
CARLOS AUGUSTO METIDIERI MENEGOZZO, SÉRGIO SAMIR ARAP, ALESSANDRO WASUM MARIANI, HÉLIO MINAMOTO, RUI IMAMURA, RICARDO FERREIRA BENTO, PAULO MANOEL PÊGO-FERNANDES, LUIZ PAULO KOWALSKI, EDIVALDO MASSAZO UTIYAMA   +8 more
doaj   +2 more sources

Teams and cardiac surgery [PDF]

, 2009
Motivation\ud Our study is designed to identify human factors that are a threat to the safety of children with heart disease.\ud \ud Research approach\ud After an initial observation period, we will apply a major safety intervention.
Barach, Paul, Schraagen, Jan Maarten, Smit, Meike, Ven, Josine van de   +3 more
core   +2 more sources

Single Test‐Based Diagnosis and Subtyping of Pulmonary Hypertension Caused by Fibrosing Mediastinitis Using Plasma Metabolic Analysis

Advanced Science, EarlyView.
Pulmonary hypertension caused by fibrosing mediastinitis has a five‐year survival rate of just 56%. Current diagnostic approaches are complex for patients with mobility limitations and can lead to misdiagnoses due to their nonspecific clinical features.
Yating Zhao, Chunmeng Ding, Hongling Su, Aqian Wang, Aiping Tang, Hongfan Zhao, Ya Ma, Min Zhang, Wanshan Liu, Ruimin Wang, Ziyue Zhang, Shouzhi Yang, Dingyitai Liang, Yida Huang, Kun Qian, Lin Huang, Qihua Fu, Yunshan Cao   +17 more
wiley   +1 more source

Video assisted thoracic surgery for treatment of pneumothorax and lung resections: systematic review of randomised clinical trials [PDF]

, 2004
<b>Objectives</b> To determine if video assisted thoracic surgery is associated with better clinical outcomes than thoracotomy for three common procedures: surgery for pneumothorax, minor resections, and lobectomy.
Lewsey, J., Sedrakyan, A., Treasure, T., van der Meulen, J.   +3 more
core   +3 more sources