Results 151 to 160 of about 249,915 (344)

Etiology and Surgical Management of Cervical Spinal Epidural Abscess (SEA):: A Systematic Review. [PDF]

, 2018
Study Design: Systematic analysis and review. Objective: Evaluation of the presentation, etiology, management strategies (including both surgical and nonsurgical options), and neurological functional outcomes in patients with cervical spinal epidural ...
,, Harrop, James, Iorio, Justin, Jallo, Jack, Mosley, MD, Yusef, Pelta-Heller, Joshua, Prasad, Srinivas, Shahrokh, Soroush   +7 more
core   +1 more source

PP2A Promotes the Symmetric Division of MUC1‐Dominant Cancer Stem‐Like Cells in Small Cell Lung Cancer

Advanced Science, EarlyView.
During the G2/M phase, mucin1 (MUC1) activates protein phosphatase 2A (PP2A), leading to reduced phosphorylation of protein kinase C ζ (PKCζ) and NUMB, which promotes symmetric division and expansion of cancer stem‐like cells (CSLCs), thereby driving tumorigenesis. Combined inhibition of the MUC1–PP2A axis using LB100/GO203 with etoposide restores PKCζ
Shengze Li, Xinran Dong, Kexing Gao, Yiyang Wang, Min Li, Huayun Deng, Shuangyu Ma, Yaping Lv, Wei Jin, Quanfu Li, Yuming Wang, Xiaodong Liao, Kangjing Bian, Aiwu Zhou, Chengping Hu, Lei Huang   +15 more
wiley   +1 more source

Leveraging Surgical Activity Grammar for Primary Intention Prediction in Laparoscopy Procedures [PDF]

arXiv
Surgical procedures are inherently complex and dynamic, with intricate dependencies and various execution paths. Accurate identification of the intentions behind critical actions, referred to as Primary Intentions (PIs), is crucial to understanding and planning the procedure.
arxiv  

Spinal column shortening versus revision detethering for recurrent adult tethered cord syndrome: a preliminary comparison of perioperative and clinical outcomes. [PDF]

, 2020
OBJECTIVE:Recurrent tethered cord syndrome (TCS), believed to result from tension on the distal portion of the spinal cord, causes a constellation of neurological symptoms. Detethering surgery has been the traditional treatment for TCS. However, in cases
Chang, Chih-Chang, Chou, Dean, Dhall, Sanjay, Gupta, Nalin, Jian, Fengzeng, Mummaneni, Praveen V, Yuan, Chenghua, Zhang, Can   +7 more
core   +1 more source

Intraoperative Fast Adaptive Focus Tracking Robotic OCT Enables Real‐Time Tumor Grading and Large‐Area Microvascular Imaging in Human Spinal Cord Surgery

Advanced Science, EarlyView.
The fast adaptive focus tracking robotic optical coherence tomography (FACT‐ROCT) offers real‐time, high‐resolution imaging of spinal cord tumors during surgery. By reducing motion artifacts with robotics and adaptive focal tracking, it accurately differentiates tumor grades using a novel attenuation coefficient marker and reveals critical ...
Bin He, Yuzhe Ying, Yejiong Shi, Zhe Meng, Zichen Yin, Zhengyu Chen, Zhangwei Hu, Ruizhi Xue, Linkai Jing, Yang Lu, Zhenxing Sun, Weitao Man, Youtu Wu, Dan Lei, Ning Zhang, Guihuai Wang, Ping Xue   +16 more
wiley   +1 more source

A Multidisciplinary Curriculum to Standardize Chest Procedures Training for Trainees in General Surgery, Emergency Medicine, and Critical Care

MedEdPORTAL
Introduction Critical care, emergency medicine, and surgical trainees frequently perform surgical and Seldinger-technique tube thoracostomy, thoracentesis, and thoracic ultrasound.
Jacob LoMonaco, Robert J. Klemisch, Jonathan S. Ilgen, Beth Sobba, Jenelle Badulak, Thomas K. Varghese, Amy E. Morris   +6 more
doaj   +1 more source

Recognize Any Surgical Object: Unleashing the Power of Weakly-Supervised Data [PDF]

arXiv
We present RASO, a foundation model designed to Recognize Any Surgical Object, offering robust open-set recognition capabilities across a broad range of surgical procedures and object classes, in both surgical images and videos. RASO leverages a novel weakly-supervised learning framework that generates tag-image-text pairs automatically from large ...
arxiv  

Neutrophil‐Mimicking Nanomedicine Eliminates Tumor Intracellular Bacteria and Enhances Chemotherapy on Liver Metastasis of Colorectal Cancer

Advanced Science, EarlyView.
Fusobacterium nucleatum (Fn) enrichment has been identified in colorectal cancer and its liver metastases. This study develops neutrophil‐mimicking nanoparticles with multiple targeting capabilities encapsulating metronidazole and oxaliplatin for antibacterial and anticancer purposes. This approach reverses the epithelial mesenchymal transition process
Yanan Niu, Xu Zhao, Yong Li, Xiaoya Ma, Weifeng Yang, Jie Ma, Wanglin Li, Wei Yuan   +7 more
wiley   +1 more source

Multi‐Omics and ‐Organ Insights into Energy Metabolic Adaptations in Early Sepsis Onset

Advanced Science, EarlyView.
This study shows that patients at risk of sepsis have a distinct metabolite and lipid signature, including serine and aminoadipic acid, in their serum before clinical diagnosis. A mouse model of sepsis with a compatible serum signature reveals underlying metabolic changes, including mitochondrial adaptation, altered serine‐dependent purine metabolism ...
Lin‐Lin Xu, Zhengyuan Zhou, Sascha Schäuble, Wolfgang Vivas, Karen Dlubatz, Michael Bauer, Sebastian Weis, Mervyn Singer, Roman Lukaszewski, Gianni Panagiotou   +9 more
wiley   +1 more source

Establishment of Mongolia's first independent and sustainable minimally invasive general thoracic surgery program: A Mongolian-Canadian initiativeCentral MessagePerspective

JTCVS Open
Objective: The advent of video-assisted thoracoscopic surgery in Mongolia has faced funding and accessibility challenges, leading to languid adoption.
Azjargal Badamkhand, MD, MHSc, MAMS, Roy A. Hilzenrat, MD, MHSc, MGSC, Ganzorig Baatar, MD, MPH, MAMS, Mergen Dugarsuren, MD, MAMS, Sharon R.Y. Ong, MD, MEd, FRCSC, Ahmad S. Ashrafi, MD, FRCSC   +5 more
doaj