Results 41 to 50 of about 2,773,111 (253)

Minimally invasive thoracic surgery: beyond surgical access

, 2018
Thoracic surgery has evolved throughout the decades. The difficulty of accessing the intrathoracic organs through the bony rib-cage has been a challenge for thoracic surgeons.
Sit, AKY, Wong, MKH, Au, TWK
core   +1 more source

Thoracic surgery in the Netherlands

, 2022
The purpose of this article, part of the Thoracic Surgery Worldwide series, is to provide a descriptive review of how thoracic surgery is organized in the Netherlands.
Hulsewé, Karel W. E., Franssen, Aimée J. P. M., de Loos, Erik R., de Loos, E.R., van den Broek, F.J.C., Heuts, Samuel, Vissers, Y.L.J., Heuts, S., Jansen, Y.J.L., Maessen, Jos G., Janssen, N., Daemen, J.H.T., Maessen, J.G., Laven, I.E.W.G., Janssen, Nicky, Hulsewe, K.W.E., Maessen, J.G.; id_orcid, Franssen, A.J.P.M., Daemen, Jean H. T., van den Broek, Frank J. C., Laven, Iris E. W. G., Jansen, Yanina J. L., Vissers, Yvonne L. J.   +22 more
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Lysyl oxidase (LOX)‐mediated remodeling of the extracellular matrix

FEBS Letters, EarlyView.
The lysyl oxidase (LOX) family of enzymes drives extracellular matrix remodeling by oxidizing collagen, elastin, and fibronectin, promoting covalent cross‐link formation. This activity regulates tissue architecture and mechanical properties, while its dysregulation contributes to fibrosis, cardiovascular disease, glaucoma, connective tissue disorders ...
Fernando Rodríguez‐Pascual, Marta Navarro‐Gutiérrez, Verónica Romero‐Albillo, Raquel Jiménez‐Sánchez   +3 more
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

Trainees Can Safely Learn Video-Assisted Thoracic Surgery Lobectomy despite Limited Experience in Open Lobectomy [PDF]

, 2015
BACKGROUND: The aim of this study was to establish whether pulmonary lobectomy using video-assisted thoracic surgery (VATS) can be safely performed by trainees with limited experience with open lobectomy. METHODS: Data were retrospectively collected from
정경영, 이창영
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En bloc vertebrectomy for the treatment of spinal lesions. Five years of experience in a single institution: a case series

Clinics, 2018
OBJECTIVES: The objective of this study is to describe the experience of a Brazilian public university hospital regarding the treatment of metastatic or benign spine lesions with en bloc vertebrectomy of the thoracic and lumbar spines.
Alex Oliveira de Araujo, Douglas Kenji Narazaki, William Gemio Jacobsen Teixeira, Cesar Salge Ghilardi, Pedro Henrique Xavier Nabuco de Araujo, Antônio Eduardo Zerati, Raphael Martus Marcon, Alexandre Fogaça Cristante, Tarcísio Eloy Pessoa de Barros Filho   +8 more
doaj   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Lifesaving and Emergency Surgical Procedures in Trauma Patients

, 2023
Damage control surgery represents a salvage procedure for trauma patients with the life-threatening triad of hypothermia, acidosis, and coagulopathy. Although nonoperative management has become the norm for many solid visceral injuries and some vascular ...
Paolo Aseni, Sharon Henry, Thomas M Scalea, Antonino Massimiliano Grande, Antonio Fiore   +4 more
core  

Early Clinical, Imaging, and Pathological Characteristics of SRPK3/TTN‐Digenic Myopathy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective SRPK3/TTN‐digenic myopathy was recently established as a skeletal muscle myopathy caused by digenic inheritance. This study characterizes the early clinical presentation of SRPK3/TTN‐digenic myopathy in one previously reported and seven newly identified pediatric patients.
Rotem Orbach, Sandra Donkervoort, Carola Hedberg‐Oldfors, Giovanni Baranello, Dimah Saade, Precilla D'Souza, Ruchee Patel, Eva Michael, A. Reghan Foley, Diana Bharucha‐Goebel, S. Jin Haugland, Meghan McAnally, Omer Abdul Hamid, Katherine Chao, Ellen F. Macnamara, Alan H. Beggs, Anna Sarkozy, Juliane Mueller, Steven A. Moore, Richard S. Finkel, Cynthia J. Tifft, Francesco Muntoni, Anders Oldfors, Carsten G. Bönnemann   +23 more
wiley   +1 more source

Lung Transplantation for Cystic Fibrosis After Thoracic Surgical Procedures

, 2011
During their life, cystic fibrosis (CF) patients may require thoracic surgical procedures for a number of reasons before undergoing lung transplantation. In the past, this has been considered to be a contraindication to lung transplantation.
T. De Giacomo, DE GIACOMO, Tiziano, ANILE, MARCO, VENUTA, Federico, RENDINA, Erino Angelo, F. Venuta, M. Anile, M. Rolla, F. Ruberto, E.A. Rendina, RUSSO, EMANUELE, E. Russo, S. Quattrucci, G. Furio Coloni, D. Diso, DISO, DANIELE, QUATTRUCCI, Serena   +16 more
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