Results 41 to 50 of about 92,971 (256)

Exposure to 100% Oxygen Abolishes the Impairment of Fracture Healing after Thoracic Trauma. [PDF]

PLoS ONE, 2015
In polytrauma patients a thoracic trauma is one of the most critical injuries and an important trigger of post-traumatic inflammation. About 50% of patients with thoracic trauma are additionally affected by bone fractures.
Julia Kemmler, Ronny Bindl, Oscar McCook, Florian Wagner, Michael Gröger, Katja Wagner, Angelika Scheuerle, Peter Radermacher, Anita Ignatius   +8 more
doaj   +1 more source

Re‐Purposing Sapropterin (Kuvan) for ACTA2‐Related Multisystemic Smooth Muscle Dysfunction Syndrome: A Translational Mechanistic and First‐In‐Human Therapeutic Report

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Multisystemic smooth muscle dysfunction syndrome (MSMDS) is an ultra‐rare, ACTA2‐related disorder characterized by severe cerebrovascular disease, aortic aneurysms, and smooth muscle dysfunction. Using molecular dynamics simulations and in silico drug screening, we identified that sapropterin dihydrochloride (Kuvan) is a candidate capable of ...
Moran Hausman‐Kedem, Noa Bielopolski, Vijai Krishnan, Shane Wald‐Altman, Shelly I Shrian, Omer Bar‐Yosef, Livia Kapusta, Claire Shamber, Patricia L. Musolino, Miguel Weil   +9 more
wiley   +1 more source

Rheumatoid arthritis, frailty, and outcomes of surgical hospitalizations: A national population‐based analysis

Arthritis Care &Research, Accepted Article.
OBJECTIVE Hospitalization, particularly for surgery, represents a period of heightened stress. We evaluated how frailty attenuates the association of rheumatoid arthritis (RA) with negative health outcomes after elective non‐cardiac surgery. METHODS We conducted a cross‐sectional study using the National Inpatient Sample (2018 to 2020), including ...
Ali Yazdanyar, Joshua Baker, Katherine D Wysham, Mohammed Yousufuddin, Farah Acher Kaiksow, Michael M. Ward   +5 more
wiley   +1 more source

[Thoracic trauma].

Il Giornale di chirurgia, 1995
From January 1989 to December 1992, in the Institute of Clinical Surgery of the University of Perugia, 102 patients were admitted for thoracic trauma. Two patients with an open thoracic trauma, both presenting multiple shot-wounds, underwent an explorative thoracotomy.
MAZIERI M, CIROCCHI, Roberto, COVARELLI, Piero, CAGINI, Lucio, BELLOCHI R, VOLPI G, FABBRI C, MOSCI F.   +7 more
openaire   +2 more sources

An Epigenetic Fate Converter Based on Nuclei‐Targeting Lipid Nanoparticles Drives Neuronal Programming of Stem Cells for Spinal Cord Repair

Advanced Functional Materials, EarlyView.
Schematic illustration of LNP‐MPG nuclei‐targeting delivery of HMW‐FGF2 promoting histone acetylation to regulate the fate of DPSCs and treat spinal cord injury. LNPs components include pHMW‐FGF2 plasmid, DSPC, Dlin‐MC3‐DMA, cholesterol, and PEG2000, and are modified with MPG to form HMW‐FGF2@LNP‐MPG (HLM). HLM nuclei‐targets DPSCs to deliver HMW‐FGF2,
Heng Zhou, Qiang Qin, Xiqin Li, Hanyu Ding, Chun Xu, Yan He, Qingsong Ye   +6 more
wiley   +1 more source

Biodegradable 3D‐Printable and Coatable Antifouling Composites for Marine Applications

Advanced Functional Materials, EarlyView.
Marine biofouling damages submerged surfaces and raises greenhouse gas emissions. Biodegradable antifouling biocomposites were developed by hot‐mixing beeswax, Tween 80, and calcium stearate or stearic acid. Adjusting the component ratio enables processing via hot‐pressing, 3D‐printing, or dip‐coating.
Gabriele Corigliano, Lorenzo Ravelli, Martina Nardi, Ruowen Tu, Elena Bellini, Valerio Isa, Carlo Filippeschi, Roberta Finazzi, Luca Ceseracciu, Niloofar Paknezhad, Vincenzo Scribano, Paolo Galli, Silvia Lavorano, Simone Montano, Barbara Mazzolai, Marco Contardi, Pietro Cataldi, Athanassia Athanassiou   +17 more
wiley   +1 more source

Evaluation of Trimethylamine N-Oxide (TMAO) Levels in Blunt Thoracic Trauma: An Experimental Study

Genel Tıp Dergisi
Background/Aims: Thoracic traumas cause life-threatening problems ranging from lung contusion to multiorgan injuries, while acute lung injury (ALI) and acute respiratory distress syndrome (ARDS) are common complications of ...
Fatma Şengül, Fikret Akyürek, Bahadir Ozturk, Hüsamettin Vatansev, Aysegül Bayır, Hasan Kara, Muslu Kazım Körez   +6 more
doaj   +1 more source

Intelligent Orthopedics: Machine Learning in Diagnosis of Bone Disease, Implants, and Bone Health Monitoring

Advanced Healthcare Materials, EarlyView.
Efficient recovery from traumatic or degenerative diseases is a great challenge, even after all the advancements in bone and cartilage regeneration. Machine learning (ML) algorithms have presented opportunities to enhance these aspects by accurately analyzing imaging data.
Maryam Kamaei, Hesam Mohammadi, Shamim Golafshan, Mojtaba Alehosseini, Mahsa Mohammadzadeh, Atefeh Golshirazi, Nasim Golafshan, Tatiane Eufrásio‐da‐Silva, Alireza Dolatshahi‐Pirouz, Gorka Orive   +9 more
wiley   +1 more source

Video-assisted thoracoscopic surgery for acute thoracic trauma

Journal of Emergencies, Trauma and Shock, 2013
Background: Operative intervention for thoracic trauma typically requires thoracotomy. We hypothesized that thoracoscopy may be safely and effectively utilized for the acute management of thoracic injuries. Materials and Methods: The Trauma Registry of a
Michael Goodman, Jaime Lewis, Julian Guitron, Michael Reed, Timothy Pritts, Sandra Starnes   +5 more
doaj   +1 more source

Experimental Model of Blunt Chest Trauma in Rats [PDF]

Journal of Biomedical & Clinical Research, 2014
The aim of the study was to present our own experimental model of blunt chest trauma in small laboratory animals. Fifteen Wistar albino rats (body weight 290.0-320.0 g) were used in the experiment.
Ivan Novakov, Delyan Delev, Svitlana Bachurska, Dmitrii Staikov   +3 more
doaj   +3 more sources