Results 51 to 60 of about 161,855 (295)

NET‐DNA Activates the ANXA2/TMEM215/BiP Axis to Promote Mitophagy‐Mediated Anoikis Resistance in Endometriosis

open access: yesAdvanced Science, EarlyView.
NET‐DNA is enriched during early endometriotic lesion establishment and drives anoikis resistance by promoting an ANXA2–TMEM215–BiP axis. This pathway strengthens ER–mitochondria contacts, enhances PINK1/Parkin‐associated mitophagy, preserves mitochondrial homeostasis, and supports ectopic stromal cell survival, thereby facilitating lesion persistence ...
Honglin Wang   +12 more
wiley   +1 more source

A new approach to investigate wave dissipation in viscoelastic tubes: Application of wave intensity analysis

open access: yes, 2005
Wave dissipation in elastic and viscoelastic medium has been investigated extensively in the frequency domain. The aim of this study is to examine the pattern of wave dissipation in the time-domain using wave intensity analysis.
J. Feng, Feng, J, Khir, AW, A.W. Khir
core   +1 more source

Using Local Flaps in a Chest Wall Reconstruction after Mastectomy for Locally Advanced Breast Cancer

open access: yesArchives of Plastic Surgery, 2015
Background Surgical ablation for locally advanced breast cancer results in large chest wall defects, which can then be managed with local flaps or skin grafts. The purpose of this article is to evaluate the outcomes of three types of local skin flaps.
Joo Seok Park   +3 more
doaj   +1 more source

A case of mesenchymal hamartoma of the chest wall of a child

open access: yesRadiology Case Reports, 2021
Mesenchymal hamartoma of the chest wall is a rare benign tumor that usually occurs in infants and children. The clinical presentations and imaging features are atypical and difficult to differentiate from malignant tumors.
Nguyen Ngoc Trung, MD, PhD   +7 more
doaj   +1 more source

Integrated Single‐Cell and Spatial Analysis Reveals a Metabolic‐Immune Axis Driving Aortic Dissection

open access: yesAdvanced Science, EarlyView.
Single‐cell and spatial profiling of 110 human thoracic aortic samples reveals a stromal–immune circuit driving aortic dissection. An elastin‐rich fibroblast subset is depleted with age and markedly reduced in disease, weakening aortic wall integrity.
Jing Tao   +25 more
wiley   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

open access: yesAdvanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu   +12 more
wiley   +1 more source

Three-dimensional sensitivity assessment of thoracic aortic aneurysm wall stress: a probabilistic finite-element study

open access: yes, 2013
OBJECTIVES: In clinical practice, maximum diameter is used as a criterion to estimate aneurysm-rupture risk; however, it is only a general indicator and its value becomes difficult to estimate in the thoracic segment.
Simona Celia   +3 more
core   +1 more source

Unusual variant of an accessory thoracic muscle

open access: yesFolia Morphologica
BACKGROUND: The anterior thoracic wall musculature presents significant morphological variability. The literature describes a few accessory thoracic muscles (ATMs) and discusses possible clinical implications. A dissection report describes an unusual ATM
George Triantafyllou   +7 more
doaj   +1 more source

An Implantable Phototriggered Prodrug Depot Patch Enables Actively Programmable Drug Release for Post‐Myocardial Infarction Therapy

open access: yesAdvanced Science, EarlyView.
An implantable phototriggered prodrug depot patch (iPDP) is presented that enables actively programmable drug release post‐implantation. Covalently conjugated prodrug ensures minimal leakage; illumination parameters serve as a code to precisely control dose per release.
Haipeng Lu   +10 more
wiley   +1 more source

Clinical Case Report: Mondor's Disease

open access: yesRevista de la Facultad de Medicina Humana, 2020
Mondor’s disease is a clinical entity characterized by the appearance of a palpable cord-like induration on the body's surface. In general it is considered as a self-limited benign thrombophlebitis that resolves in four or eight weeks without any ...
Edilberto Temoche Espinoza   +2 more
doaj   +1 more source

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