Results 141 to 150 of about 91,163 (292)

Inaccurate clinical nodal staging of non-small-cell lung cancer: evidence fro mthe MRC LU22 multicentre randomised trial [PDF]

open access: yes, 2010
Gilligan, D   +7 more
core   +1 more source

A Novel Approach to Cadaver‐Based Soiled Airway Simulation

open access: yesAEM Education and Training, Volume 10, Issue 3, June 2026.
ABSTRACT Effective management of heavily soiled airways is a critical and challenging skill across multiple clinical settings. Existing training methods rely largely on manikin‐based simulators, which often lack sufficient anatomical realism and haptic fidelity.
Adam Parks   +3 more
wiley   +1 more source

P2X7 receptors promote atrial remodeling and atrial fibrillation susceptibility via reactive oxygen species‐mediated mitogen‐activated protein kinase signaling activation

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Abstract Atrial fibrillation (AF), the most common clinical arrhythmia, is driven by inflammatory activation and oxidative stress, though precise molecular links remain unclear. This study identifies the P2X7 receptor as a key upstream regulator orchestrating proarrhythmic atrial remodeling through reactive oxygen species (ROS)‐mediated mitogen ...
Lingnan Zhang, Yeran Zhu, Xinshun Gu
wiley   +1 more source

Structural Characterization of Cardiac Free‐Running Purkinje Fibers Using Inhomogeneous Magnetization Transfer (ihMT): A Proof of Concept MRI‐Histology Approach

open access: yesNMR in Biomedicine, Volume 39, Issue 6, June 2026.
The cardiac Purkinje network is essential for synchronized ventricular activation but remains difficult to visualize with conventional MRI due to limited structural contrast. This study demonstrates that inhomogeneous magnetization transfer imaging provides enhanced contrast that differentiates free‐running Purkinje fibers, Purkinje‐Myocardial Junction,
Arash Forodighasemabadi   +11 more
wiley   +1 more source

Tissue‐retained needles in people who inject drugs: A systematic review of case reports and series on clinical presentations, complications and management

open access: yesAddiction, Volume 121, Issue 6, Page 1381-1397, June 2026.
Abstract Background and aims Tissue‐retained needles from intravenous drug use can cause rare but severe complications, ranging from local to systemic infections to needle embolization. Due to the limited evidence and the lack of epidemiological studies on the issue, we systematically reviewed the literature focusing on case reports and case series on ...
Heidi Laukkala   +7 more
wiley   +1 more source

Advances and Future Perspectives for the Management of Non‐Small Cell Lung Cancer in Australia: A Narrative Review

open access: yesAsia-Pacific Journal of Clinical Oncology, Volume 22, Issue 3, Page 333-350, June 2026.
Lung cancer remains Australia's leading cause of cancer death. With new screening and evolving therapies, equitable access and workforce readiness are essential. This review discusses current and emerging treatments for NSCLC in Australia, clinical trials underway, and future directions in delivering optimal, accessible care nationwide.
Lauren Julia Brown   +7 more
wiley   +1 more source

Thrombospondin‐4 is upregulated in abdominal aortic aneurysm: A vasoprotective response with potential therapeutic relevance

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 12, Page 3321-3339, June 2026.
TSP4 is upregulated in human and experimental AAA. TSP4 knockdown accelerated AAA formation and exacerbated both vascular inflammation and remodelling, emphasizing that TSP4 upregulation may represent a protective response against AAA. Our findings suggest that preserving TSP4 could be a useful strategy in the clinical management of AAA.
Laia Blanco‐Casoliva   +10 more
wiley   +1 more source

Elevated ASGR1 as a Potential Diagnostic Biomarker for Coronary Artery Disease and Predictor of Adverse Outcomes in Hypertensive Patients

open access: yesThe FASEB Journal, Volume 40, Issue 9, 15 May 2026.
Asialoglycoprotein receptor 1 (ASGR1) is linked to lipid metabolism and CAD, but its role in hypertensive CAD patients is unclear. This single‐center study included 345 hypertensive patients (59 non‐CAD, 286 CAD). Plasma ASGR1 was higher in CAD patients, correlated with multiple markers and HDL‐C, had high diagnostic value (better than traditional ...
Ying Liu   +12 more
wiley   +1 more source

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