Results 71 to 80 of about 450,295 (383)

Effects of Prior Psychosocial Trauma on Subsequent Immune Response After Experimental Thorax Trauma

Shock, 2017
Overshooting inflammation during the early phase after blunt thorax trauma promotes the development of acute respiratory distress syndrome, multiple organ failure, and subsequent mortality.
D. Langgartner, Annette Palmer, Anne Rittlinger, S. Reber, M. Huber-Lang   +4 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

hERG S4-S5 linker acts as a voltage-dependent ligand that binds to the activation gate and locks it in a closed state

Scientific Reports, 2017
Delayed-rectifier potassium channels (hERG and KCNQ1) play a major role in cardiac repolarization. These channels are formed by a tetrameric pore (S5–S6) surrounded by four voltage sensor domains (S1-S4).
Olfat A. Malak, Zeineb Es-Salah-Lamoureux, Gildas Loussouarn   +2 more
doaj   +1 more source

Recommendations for Standardizing Thorax PET–CT in Non-Human Primates by Recent Experience from Macaque Studies

Animals, 2021
Despite the possibilities of routine clinical measures and assays on readily accessible bio-samples, it is not always essential in animals to investigate the dynamics of disease longitudinally.
Marieke A. Stammes, Jaco Bakker, Richard A. W. Vervenne, Dian G. M. Zijlmans, Leo van Geest, Michel P. M. Vierboom, Jan A. M. Langermans, Frank A. W. Verreck   +7 more
doaj   +1 more source

Semiaquatic Hemiptera of Wisconsin [PDF]

, 2017
Twenty-six species in five families of semi aquatic Hemiptera were collected in Wis­consin and as many as four more may occur. Keys to all of these species are provided along with notes on their distribution, abundance, and identification.
Hilsenhoff, William L
core   +1 more source

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

Feasibility of a ctDNA multigenic panel for non‐small‐cell lung cancer early detection and disease surveillance

Molecular Oncology, EarlyView.
Plasma‐based detection of actionable mutations is a promising approach in lung cancer management. Analysis of ctDNA with a multigene NGS panel identified TP53, KRAS, and EGFR as the most frequently altered, with TP53 and KRAS in treatment‐naïve patients and TP53 and EGFR in previously treated patients.
Giovanna Maria Stanfoca Casagrande, Marcela de Oliveira Silva, Mariana Bisarro dos Reis, Rodrigo de Oliveira Cavagna, Luciane Sussuchi, Icaro Alves Pinto, Natalia Zampieri Pontes, Rodrigo Sampaio Chiarantano, Flavio Augusto Ferreira da Silva, Pedro de Marchi, Letícia Ferro Leal, Rui M. Reis   +11 more
wiley   +1 more source

Screening for lung cancer: A systematic review of overdiagnosis and its implications

Molecular Oncology, EarlyView.
Low‐dose computed tomography (CT) screening for lung cancer may increase overdiagnosis compared to no screening, though the risk is likely low versus chest X‐ray. Our review of 8 trials (84 660 participants) shows added costs. Further research with strict adherence to modern nodule management strategies may help determine the extent to which ...
Fiorella Karina Fernández‐Sáenz, Laura de la Torre‐Perez, David R Baldwin, Carlijn van der Aalst, Mangesh Thorat, David Ritchie, Andre L Carvalho, Carolina Espina, Ivan Solà, Carlos Canelo‐Aybar, Moira Magdalena Pissinis, Pablo Alonso‐Coello, Ana Carolina Pereira Nunes Pinto   +12 more
wiley   +1 more source

O-GlcNAcylation levels remain stable regardless of the anaesthesia in healthy rats

Scientific Reports
Anaesthetics are used daily in human and veterinary medicine as well as in scientific research. Anaesthetics have an impact on cell homeostasis especially through modulation of protein post-translational modifications.
Thomas Dupas, Amandine Vergnaud, Thomas Pelé, Angélique Blangy-Letheule, Virginie Aillerie, Martin Bouaud, Angélique Erraud, Anaïs Maillard, Dorian Hassoun, Antoine Persello, Jules Lecomte, Matthieu Rivière, Arnaud Tessier, Aurélia A. Leroux, Bertrand Rozec, Manon Denis, Benjamin Lauzier   +16 more
doaj   +1 more source

Biventricular / Left Ventricular Pacing in Hypertrophic Obstructive Cardiomyopathy: An Overview

Indian Pacing and Electrophysiology Journal, 2012
Hypertrophic cardiomyopathy (HCM) is an autosomal dominant inherited genetic disease characterized by compensatory pathological left ventricle (LV) hypertrophy due to sarcomere dysfunction.
Radu Vatasescu, MD, Reinder Evertz, MD, Lluis Mont, MD, PhD, Marta Sitges, MD, PhD, Josep Brugada, MD, PhD, Antonio Berruezo, MD, PhD   +5 more
doaj   +1 more source