Results 211 to 220 of about 67,828 (287)

GPCRs in CAR‐T Cell Immunotherapy: Expanding the Target Landscape and Enhancing Therapeutic Efficacy

Advanced Science, EarlyView.
Chimeric antigen receptor T cell therapy faces dual challenges of target scarcity and an immunosuppressive microenvironment in solid tumors. This review highlights how G protein‐coupled receptors can serve as both novel targets to expand the therapeutic scope and functional modules to enhance CAR‐T cell efficacy.
Zhuoqun Liu, Yuchen Xiao, Yamin Zhao, Lihe Dai, David J.H. Shih, Shikang Liang, Honglei Tian, Liu Liu, Feng Tian, Bing Liu, Lei Chang, Chao Zhang   +11 more
wiley   +1 more source

Variability of ¹³⁷Cs and natural radionuclides accumulation in mosses relative to soil activity in Iğdır, Türkiye. [PDF]

Front Plant Sci
Batan N, Büyükuslu H, Akçay N.
europepmc   +1 more source

Linearizing and Forecasting: A Reservoir Computing Route to Digital Twins of the Brain

Advanced Science, EarlyView.
A new approach uses simple neural networks to create digital twins of brain activity, capturing how different patterns unfold over time. The method generates and recovers key dynamics even from noisy data. When applied to fMRI, it predicts brain signals and reveals distinctive activity patterns across regions and individuals, opening possibilities for ...
Gabriele Di Antonio, Tommaso Gili, Andrea Gabrielli, Maurizio Mattia   +3 more
wiley   +1 more source

The effect of operational parameters on the properties of thorium uranium oxide produced via oxalates' coprecipitation. [PDF]

Sci Rep
Bagheri N, Nosratinia F, Zahakifar F, Yousefi T.   +3 more
europepmc   +1 more source

Self‐Assembling Hybrid Hydrogel Reprograms the Stromal Vascular Fraction to Treat Osteoarthritis

Advanced Science, EarlyView.
This study presents a bioinspired injectable hydrogel that enhances the therapeutic potential of stem cell‐rich stromal vascular fraction for treating osteoarthritis. By reprogramming cell behavior through epigenetic modulation, the hydrogel promotes cartilage regeneration and reduces joint damage in a rat model, offering a promising new approach for ...
Waifang Hou, Yongfeng Chen, Longyou Xiao, Wei Qi, Tianshu Du, Qiang Sun, Borui Xue, Qinghe Zhao, Pengfei Xie, Zi Ye, Fei Han, Lingli Guo, Yang Jiao, Ranran Zhang, Hong Jia, Xiao Huang, Jianwei Guo, Peng Wang, Huayi Wang, Yuanrui Wang, Wenjing Chen, Haining Wu, Liumin He, Dawei Zhang   +23 more
wiley   +1 more source

Maternal geophagy in Ghana: a mini review of toxicological, microbial, nutritional, and radiological exposure pathways. [PDF]

Front Public Health
Lawluvi H, Arwui CC, Beinpuo ESW, Faanu A, Agyeman L, Akrobortu E, Amarh T.   +6 more
europepmc   +1 more source

Solid Harmonic Wavelet Bispectrum for Image Analysis

Advanced Science, EarlyView.
The Solid Harmonic Wavelet Bispectrum (SHWB), a rotation‐ and translation‐invariant descriptor that captures higher‐order (phase) correlations in signals, is introduced. Combining wavelet scattering, bispectral analysis, and group theory, SHWB achieves interpretable, data‐efficient representations and demonstrates competitive performance across texture,
Alex Brown, Mathilda Avirett‐Mackenzie, Carolin Villforth, Georgios Exarchakis   +3 more
wiley   +1 more source

Sub-epsilon natural ²³⁴U/²³⁸U measurements refine the ²³⁴U half-life and U-Th geochronology. [PDF]

Sci Adv
Hu HM, Shen CC, Cheng H, Woodhead JD, Edwards RL, Zhao JX, Huang CY, Lu PY, Chien WY, Wang J, Jia X, Yokoyama Y, Cai Y, Zachariáš J.   +13 more
europepmc   +1 more source

Perspective: Hollow Core Optical Fibres for Ultraviolet and Visible Wavelengths

Advanced Science, EarlyView.
Hollow core optical fibres bypass material constraints that limit optical fibres at ultraviolet and visible wavelengths. However, their challenging fabrication has limited their development, and significant gains in performance remain possible. In this perspective we outline approaches to enable the next generation of fibres for shorter wavelengths ...
Robbie Mears, Kerrianne Harrington, Jonathan C. Knight, William J. Wadsworth, James M. Stone, Tim A. Birks   +5 more
wiley   +1 more source

Investigating the soil surface properties behind elevated natural radiation in Mamuju, Indonesia. [PDF]

Sci Rep
Abdullah ARA, Permana S, Srigutomo W, Maulana A, Irwanto D, Seno H, Purnama DS, Wafda H, Wulandari C, Wahyudi W, Farid MM, Rosianna I, Humolungo I, Zulfahmi Z, Nugraha ED.   +14 more
europepmc   +1 more source