Results 41 to 50 of about 67,496 (286)

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

A Thorium(IV) metallacyclopropyne complex

Nature Communications
Actinide metallacyclic chemistry  has been of interest due to its involvement  in various chemical processes. However, fundamental understanding on the key species, actinide metallacyclic complexes, is limited to metallacyclopropenes whereas little is ...
Xiuting Chen, Songpeng Wan, Qian Wang, Yu Gong   +3 more
doaj   +1 more source

Octant overlapping and angle-energy group expanded KBA parallelism of three-dimensional discrete ordinate method

Frontiers in Energy Research
IntroductionTo enhance the parallel efficiency of the conventional KBA spatial decomposition method, this study incorporates octant overlapping and angle-energy group expansion into the source iteration scheme for solving the discrete ordinate equations ...
Jian Guo, Jian Guo, Yang Zou, Yang Zou, Xuechao Zhao, Xuechao Zhao, Rui Yan, Rui Yan   +7 more
doaj   +1 more source

Domain associated with zinc fingers‐containing NF90‐NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity

FEBS Open Bio, EarlyView.
NF90–NF45 functions as a negative regulator of methyltransferase‐like 3/14 (METTL3/14)‐mediated N6‐methyladenosine (m6A) modification on primary microRNAs (pri‐miRNAs). NF90–NF45 binds to anti‐oncogenic pri‐miRNAs and inhibits their m6A modification, thereby suppressing the biogenesis of anti‐oncogenic miRNAs.
Takuma Higuchi, Shunsuke Morioka, Keiko Morisawa, Kazutsugu Matsukawa, Shingo Ashida, Takeshi Suzuki, Shuji Sakamoto   +6 more
wiley   +1 more source

Experimental heat transfer performance of a drainage-integrated fluoride salt-to-salt heat exchanger

Results in Engineering
This study experimentally investigates a novel shell-and-tube fluoride Salt-to-Salt Heat Exchanger (SSHX) with triangular drainage ports integrated into segmental baffles to enable complete passive drainage.
Qi-Ming Li, Yao Fu, Jian Tian, Chong Zhou, Yang Zou, Yuan Fu, Jie Hou, Xiao-Han Yu, Hong-Jie Xu   +8 more
doaj   +1 more source

Coupled Analysis of Thorium-based Fuels in the High-Performance Light Water Reactor Fuel Assembly

Atom Indonesia, 2021
One of the six selected concepts to be part of Generation IV nuclear reactors is the Supercritical Light Water Cooled Reactor. The High-Performance Light Water Reactor (HPLWR) is the European version and it is a very promising design.
Y. Pérez, C. R. García, F. L. Mena, L. Castro   +3 more
doaj   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

The Removal of Uranium and Thorium from Aqueous Solutions Onto by-pass Cement Dust (BCD)

Eurasian Chemico-Technological Journal, 2009
The adsorption behavior of uranium and thorium from aqueous solutions by By-pass cement dust (BCD) has been investigated by a batch technique. The uranium and thorium adsorption on BCD was studied as a function of initial concentration, weight of BCD, pH,
M. Ali Omnia, H. H. El-Kashif, S. A. Sayed, M. E.H. Shalabi   +3 more
doaj   +1 more source

Determination of Uraniumand Thorium in Sandstone Uranium Deposits by Inductively Coupled Plasma-Optical Emission Spectrometry with Microwave Digestion

Yankuang ceshi, 2022
BACKGROUND Sandstone-type uranium deposits are important strategic mineral resource. Rapid and accurate analysis of uranium and thorium content is of great significance to the evaluation and comprehensive utilization of this type of deposit.
ZHANG Lijuan, FANG Pengda, WANG Liqiang, WANG Jiasong   +3 more
doaj   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source