Results 41 to 50 of about 10,735 (306)

A 17 Year Old With Developmental Delay Presenting With Increasing Confusion and Imbalance

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Methylmalonic acidemia is an autosomal recessive genetic disorder primarily caused by defects in methylmalonyl‐CoA mutase and cobalamin (vitamin B12) metabolism. These defects disrupt the tricarboxylic acid cycle and oxidative phosphorylation, leading to the abnormal accumulation of metabolic products such as methylmalonic acid, propionic acid,
Wei Zhao, Yingli Zhang, Hongliang Zheng
wiley   +1 more source

G3BP1 Succinylation at K413 is Critical for Cardiac Function by Modulating PI3K‐AKT‐mTOR Signal Axis

open access: yesAdvanced Science, EarlyView.
Schematic illustrating the impact of G3BP1 succinylation at K413 on cardiac function. In the healthy human heart, G3BP1 succinylation maintains homeostatic mTOR signaling. In patients with dilated cardiomyopathy (DCM) and heart failure (HF), G3BP1 de‐succinylation induces RagA expression and disrupts the binding of the TSC1/2 complex, leading to the ...
Yuan Zhang   +9 more
wiley   +1 more source

Analysis of Failure to Finish a Race in a Cohort of Thoroughbred Racehorses in New Zealand

open access: yesAnimals, 2016
The objective was to describe the incidence of failure to finish a race in flat-racing Thoroughbreds in New Zealand as these are summary indicators of falls, injuries and poor performance.
Jasmine Tanner   +5 more
doaj   +1 more source

Dietary Iron Unlikely to Cause Insulin Resistance in Horses

open access: yesAnimals, 2022
Racehorses are often supplemented extra iron with the expectation that the iron will improve overall performance and health. A survey of 120 U.S. Thoroughbred trainers, representing 1978 Thoroughbreds from various regions of the U.S., was conducted to ...
Nancy L. McLean   +2 more
doaj   +1 more source

Yard differences in training, management and orthopedic injury in showjumping, riding school, and thoroughbred race horses [PDF]

open access: yes, 2012
Musculoskeletal injuries are a major cause of wastage in Thoroughbred racing and equestrian sport. Epidemiological studies in racehorses have demonstrated that risk of injury vary between trainers and with differences in training regimens, but few ...
Lönnell, Cecilia
core  

Achieving High‐Density and Stress‐Resilient Maize Breeding Via Germplasm Innovation

open access: yesAdvanced Science, EarlyView.
Global population growth and climate change have exacerbated the global food crisis. This perspective presents a conceptual framework focusing on enhancing population advantages. Several novel breeding objectives are proposed to improve density tolerance and stress resistance for yield improvement.
Xinlong Li   +9 more
wiley   +1 more source

Bem-estar em equinos do Jockey Club do Paraná: indicadores clínicos, etológicos e ritmo circadiano do cortisol

open access: yesPesquisa Veterinária Brasileira
RESUMO: Com o objetivo de estudar parâmetros indicativos de bem-estar, 30 equinos de corrida foram avaliados quanto ao temperamento, comportamento, parâmetros clínicos (condição geral, escoriações, escore corporal, cólicas no último ano, frequências ...
Lilian A. Gontijo   +6 more
doaj   +1 more source

Environmental Insights and Sustainability Opportunities for Scaled‐Up MXene Production Without Etching

open access: yesAdvanced Science, EarlyView.
Through a systematic and comprehensive analysis of the environmental impacts for the emerging MXene synthesis pathways, this study presents process transformation and optimization opportunities for low‐carbon MXene production from laboratory to industrial scales.
Yushuai Huang   +6 more
wiley   +1 more source

Responding to Risk: Regulation or Prohibition? New Zealand Media Reporting of Thoroughbred Jumps Racing 2016–2018

open access: yesAnimals, 2019
Jumps racing involves a higher risk of accident and fatality than flat racing. The wide accessibility of media, combined with alternate views regarding the place of animals in society, raises the question of the acceptability of the continuation of jumps
Kylie A. Legg   +3 more
doaj   +1 more source

A genome scan for positive selection in thoroughbred horses. [PDF]

open access: yesPLoS ONE, 2009
Thoroughbred horses have been selected for exceptional racing performance resulting in system-wide structural and functional adaptations contributing to elite athletic phenotypes.
Jingjing Gu   +6 more
doaj   +1 more source

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