Results 121 to 130 of about 1,224,762 (298)
Advanced Science, EarlyView.Metabolic adaption presents a vital survival strategy for E. multilocularis. This study identifies EmPDK as a central metabolic regulator governing glucose metabolic reprogramming. Oxidative stress activates EmHIF1α to induce EmPDK expression. Mechanistic characterization reveals this ROS/EmHIF1α/EmPDK axis drives glycolytic reprogramming to sustain ...
Huijuan Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.Corramycin, a myxobacterial natural product antibiotic, exhibits potent bactericidal activity against multidrug‐resistant Mycobacterium tuberculosis. The compound hijacks bacterial transporters such as BacA and OppABCD to enter the cell and inhibits DNA synthesis through a previously unrecognized mode of DNA gyrase poisoning, locking the enzyme in an ...
Franziska Fries +25 more
wiley +1 more source
Lyle Preslar of Minor Threat, San Pedro, California, July 11, 1982
, 1982 A photograph by Kevin Salk of Minor Threat guitarist Lyle Preslar performing at Dancing Waters in San Pedro, California on July 11 ...
Salk, Kevin
core
Centrum Antyterrorystyczne ABW w zwalczaniu terroryzmu [PDF]
Przegląd GeopolitycznyModern terrorism is a threat affecting the security of EU Member States. The article attempts to formulate an answer to the question, what threat do terrorist attacks pose to the EU and how do they affect its security after 2001?
Arkadiusz Machniak
doaj
Advanced Science, EarlyView.Schematic diagrams illustrating the breakthrough in the screening of AChE inhibitors from LBL, and the research process of the pharmacodynamics of the NCP are presented. ABSTRACT Current Alzheimer's drugs exhibit limited effectiveness, highlighting the necessity for multi‐target treatments.
Yuping Sa +11 more
wiley +1 more source
China's Competitive Threat to Latin America: An Analysis for 1990-2002 [PDF]
This paper explores China's competitive threat to Latin America in trade in manufactures. The direct threat in exports to third country markets appears small: LAC's trade structure is largely complementary to that of China.
Sanjaya Lall (QEH) and John Weiss
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Advanced Science, EarlyView.This study developed an efficacy assessment platform that integrates patient‐derived gastric cancer organoids, atomic force microscopy (AFM)‐based nanomechanical vibration detection, deep learning analysis, and organoid mechanical modeling. It detects picomolar drug effects within 0.1 s signal, achieves 97% classification accuracy, and offers non ...
Ting Zhang +10 more
wiley +1 more source
Evaluating the “Threat” Effects of Grade Repetition. Exploiting the 2001 Reform by the French-Speaking Community of Belgium [PDF]
Like active labour market programmes (ALPMs), grade repetition could generate two types of effects. Better/worse outcomes due to programme participation (i.e. the fact that pupils repeat a particular grade).
Vincent VANDENBERGHE, Michèle BELOT
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Advanced Science, EarlyView.A synergetic surface bond competition−hybridization approach was developed to synthesize high‐performance CO2 adsorbents and syngas production photocatalysts via the sulfurization‐driven control of surface basicity and interfacial coupling. The ZnIn2S4−sulfur‐doped MgO/MgAl2O4 nanocomposites showed outstanding photocatalytic efficiency for production ...
Dong Wook Lee +9 more
wiley +1 more source
Jeff Nelson of Minor Threat performs at Cathay de Grande, Los Angeles, California, April 3, 1983
, 1983 Jeff Nelson, drummer for the Washington, D.C. hardcore punk band Minor Threat, performs at Cathay de Grande in Los Angeles, California on April 3, 1983.
Salk, Kevin
core