Results 31 to 40 of about 986,909 (315)
Vaccination against Q Fever for biodefense and public health indications
Coxiella burnetii is the etiological agent of Q Fever, a disease that is often spread to humans via inhalational exposure to the bacteria from contaminated agricultural sources.
Sara eRuiz, Daniel N Wolfe
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Digitalization and Cyber Risks
Digitalization, considered in a broad sense as the most important modern trend of social development, is generally accompanied not only by positive consequences for the economy and society, but also by challenges, threats, as well as negative ...
V. G. Khalin, G. V. Chernova
doaj +1 more source
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Bisphenol A (BPA), a common chemical in plastics, exerts dual effects on bladder cancer cells: low doses promote growth and migration, while high doses suppress growth and migration. Multi‐omics and bioinformatics reveal BPA acts via MAPK and inflammatory pathways.
Shaomin Niu +10 more
wiley +1 more source
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani +6 more
wiley +1 more source
Antimicrobial resistance (AMR) is an urgent and complex global health threat, widely recognized as a silent pandemic that erodes the effectiveness of existing countermeasures and exacerbates vulnerabilities across systems.
Francesca de Rosa +3 more
doaj +1 more source
Towards Sustainable Aquaculture: A Brief Look into Management Issues
Aquaculture’s role has expanded over the past two decades, with the industry contributing to nearly 50% of the overall fish production. Aquaculture production in Asia and Africa contributes a significant share of total global aquaculture output growth ...
Noorashikin Md Noor +1 more
doaj +1 more source
Threat, prejudice and stereotyping in the context of Japanese, North Korean, and South Korean intergroup relations. [PDF]
Integrated threat theory, realistic conflict theory, and group justification (based on social identity theory) were evaluated in the international context of Japanese prejudice toward North Korea and South Korea. Military threat emerged as an important
Christian, Julie +3 more
core
Intelligent Tutoring Systems for Adult Learning in STEM Disciplines
ABSTRACT Intelligent tutoring systems (ITS) are reshaping adult learning in STEM by providing adaptive, data‐driven instruction across classrooms, workplaces, and informal environments. In the context of ITS, this article compares generative AI, which creates personalized explanations and practice materials, with explainable AI, which focuses on ...
Jill Zarestky, Amanda R. Lager Gleason
wiley +1 more source

