Results 101 to 110 of about 64,512 (218)

A Multifaceted Interplay Among Hemophagocytosis, Interleukin‐18, and Type I Interferon Distinguishes Still Disease From Other Autoinflammatory Diseases

Arthritis &Rheumatology, EarlyView.
Objective The unknown pathophysiology and the lack of specific features for systemic juvenile idiopathic arthritis and adult‐onset Still disease (collectively known as Still disease; SD) delay diagnosis and appropriate treatment. The goal of this study was to identify features and mechanisms that distinguish SD from other systemic autoinflammatory ...
Yvonne M. Mueller, Charlotte Girard, Harmen J. G. van de Werken, Stefan J. Erkeland, Dwin G. B. Grashof, Laurie Vaillant, Renske J. H. den Dekker, Iris van Zuijen, Sharon Veenbergen, Fanny Coffin, Eric Bindels, Yvan Jamilloux, Katerina Laskari, Vassili Soumelis, Bruno Fautrel, Cem Gabay, Peter D. Katsikis   +16 more
wiley   +1 more source

DNA barcode reveals occurrence of threatened species and hidden diversity on Teleost fish trade in the Coastal Amazon. [PDF]

Sci Rep, 2023
Santana P, Martins T, Lutz Í, Miranda J, da Silva R, Mesquita D, Martins R, Veneza I, Vallinoto M, Sampaio I, Evangelista-Gomes G.   +10 more
europepmc   +1 more source

IgG Glycosylation‐Dependent CLEC7A Signaling Drives Podocyte Dysfunction in Lupus Nephritis

Arthritis &Rheumatology, EarlyView.
Objective Lupus nephritis (LN) is a severe complication of systemic lupus erythematosus (SLE) that can lead to end‐stage kidney disease and increased mortality. IgG from patients with LN displays abnormal glycosylation, contributing to podocyte injury.
Rohit Upadhyay, Alexia Orellana, George C. Tsokos, Rhea Bhargava   +3 more
wiley   +1 more source

Linking life history to landscape for threatened species conservation in a multiuse region. [PDF]

Conserv Biol, 2023
Shaw RE, Spencer PB, Gibson LA, Dunlop JA, Kinloch JE, Mokany K, Byrne M, Moritz C, Davie H, Travouillon KJ, Ottewell KM.   +10 more
europepmc   +1 more source

Immunoinformatics‐Based Design of a Multi‐Epitope Vaccine Targeting a Conserved Copper–Associated Protein in Neisseria gonorrhoeae

Biotechnology and Applied Biochemistry, EarlyView.
ABSTRACT Neisseria gonorrhoeae poses an urgent public health challenge due to rapidly increasing antimicrobial resistance and the absence of an effective vaccine. Targeting conserved bacterial pathways involved in essential physiological processes may provide new opportunities for vaccine antigen discovery.
Sinethemba H. Yakobi, Uchechukwu U. Nwodo   +1 more
wiley   +1 more source

Accelerometry reveals limits to use of an energy-saving anthropogenic food source by a threatened species: A case of Carnaby's cockatoos (Zanda latirostris) and canola. [PDF]

Ecol Evol, 2023
Riley KJ, Warren K, Armstrong N, Yeap L, Dawson R, Mawson PR, Saunders DA, Cooper CE, Shephard JM.   +8 more
europepmc   +1 more source

Non‐model plants: Challenges and solutions

Applications in Plant Sciences, EarlyView.
José M. Cunill‐Flores, Guanjing Hu, Aarón I. Vélez‐Ramírez   +2 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Spatially explicit power analysis reveals challenges for a long-term threatened species monitoring program in Australia. [PDF]

Ecol Appl
Menon V, Southwell D, Robley A, Rees MW, Wilkinson DP, Giljohann K, Pascoe J, Wintle B, Hradsky BA.   +8 more
europepmc   +1 more source

Changes in mean body size in an expanding population of a threatened species. [PDF]

Proc Biol Sci, 2022
Hays GC, Taxonera A, Renom B, Fairweather K, Lopes A, Cozens J, Laloë JO.   +6 more
europepmc   +1 more source