Results 221 to 230 of about 416,543 (356)

A spatial planning approach for the identification of critical habitat for threatened species. [PDF]

open access: yesConserv Biol
Morán-Ordóñez A   +10 more
europepmc   +1 more source

Occurrences of Threatened Species included in the Third Edition of the Red Data Book of the Komi Republic (Russia). [PDF]

open access: yesBiodivers Data J, 2021
Degteva S   +55 more
europepmc   +1 more source

Research Progress on Idebenone in Neurodegenerative Diseases

open access: yesAGING MEDICINE, EarlyView.
The study not only summarizes the biological properties of Idebenone (IDE), including its role in improving mitochondrial function and antioxidative stress, but also explores its clinical research progress in various neurodegenerative diseases, providing a new perspective for the treatment of these disorders.
Yanqing Zhang   +10 more
wiley   +1 more source

Inactivation of the Burkholderia Toxin Malleicyprol by Enzymatic Cyclopropanol Ring Opening

open access: yesAngewandte Chemie, EarlyView.
Burkholderia pseudomallei and Burkholderia mallei are dangerous pathogens that cause severe diseases with high mortality rates. Their virulence relies in part on malleicyprols, potent toxins containing a highly reactive cyclopropanol group. In this study, we identify BurK, a heme‐dependent oxidoreductase that neutralizes malleicyprols by enzymatically ...
Jonas Fiedler   +4 more
wiley   +2 more sources

The estimated cost of preventing extinction and progressing recovery for Australia's priority threatened species. [PDF]

open access: yesProc Natl Acad Sci U S A
Ward M   +14 more
europepmc   +1 more source

Optimizing the dengue virus infection mouse model: Comparing different backgrounds and infection route for enhanced stability

open access: yesAnimal Models and Experimental Medicine, EarlyView.
Optimized dengue fever animal model: IFNAR−/− BALB/c mice with intraperitoneal injection. Background screening: Between IFNAR−/− (BALB/c, C57BL/6) and AG129 mice, IFNAR−/−BALB/c exhibited the most severe symptoms: (1) highest weight loss and clinical scores; (2) peak viremia (5.44 log10 RNA copies/mL, day 4); (3) significant organ damage (liver/brain ...
Dan Liao   +9 more
wiley   +1 more source

Fluorescent Probes Derived from the Polyene Class of Antifungal Drugs Reveal Distinct Localization Patterns and Resistance‐Associated Vacuolar Sequestration in Candida Species

open access: yesAngewandte Chemie, EarlyView.
Fluorescent probes derived from all three clinically used polyene antifungals (amphotericin B, nystatin, and natamycin) enabled direct visualization of distribution in yeast cells of various Candida species. While retaining the ergosterol‐dependent mode of action of their parent drugs, the probes revealed distinct, structure‐specific localization ...
Melissa Shbeta   +6 more
wiley   +2 more sources

Policy decisions matter: Cessation of logging benefits 34 threatened species in Victoria, Australia. [PDF]

open access: yesPLoS One
Ashman KR   +12 more
europepmc   +1 more source

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