Results 281 to 290 of about 400,851 (354)

First‐in‐human safety, tolerability, pharmacokinetics and pilot food‐effect study of the candidate antimalarial compound MMV367

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Aim To evaluate the safety, tolerability and pharmacokinetics in healthy participants of orally administered MMV367 (GSK3772701), a novel antimalarial interfering with Plasmodium falciparum acyl coenzyme A synthetase 10/11 function. Methods This first‐in‐human study enrolled 47 healthy male and female participants.
Andrea Kuemmerle   +13 more
wiley   +1 more source

Coral Restoration in the Omics Era: Development of Point‐of‐Care Tools for Monitoring Disease, Reproduction, and Thermal Stress

open access: yesBioEssays, EarlyView.
Shown are different multi‐omics approaches that are used to identify potential biomarkers of coral health and disease. The integration of these data streams, using cutting‐edge molecular diagnostic technologies, including colorimetric dipsticks, lateral flow assays, and colorimetric LAMP (loop‐mediated isothermal amplification), holds the promise to ...
Erin E. Chille   +8 more
wiley   +1 more source

Home - About - Disclaimer - Privacy