Results 61 to 70 of about 4,919,976 (365)

Insights into PI3K/AKT signaling in B cell development and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
This Review explores how the phosphoinositide 3‐kinase and protein kinase B pathway shapes B cell development and drives chronic lymphocytic leukemia, a common blood cancer. It examines how signaling levels affect disease progression, addresses treatment challenges, and introduces novel experimental strategies to improve therapies and patient outcomes.
Maike Buchner
wiley   +1 more source

Half a century of survey data reveal population recovery but persistent threats for the Vulnerable yellow-footed rock-wallaby in Queensland, Australia

Oryx
The record of mammal declines and extinctions in Australia raises concerns regarding geographically restricted and poorly known taxa. For many taxa, the existing data are insufficient to assess their conservation status and inform appropriate management.
Jennifer Lesley Silcock, Ian C. Gynther, Alan Horsup, Jenny Molyneux, Tracy L. Wattz, Russell J. Fairfax, Al J. Healy, David Murphy, Peter D. McRae   +8 more
doaj   +1 more source

Current State of Conservation Knowledge on Threatened Amphibian Species in Peru [PDF]

, 2008
This study documents the current state of conservation knowledge on threatened amphibian species in Peru. Following the International Union for the Conservation of Nature (IUCN) classification system, we considered species in the following categories ...
Angulo, Ariande, Brown, Jason L., Carrillo, Jorge, Catenazzi, Alessandro, Chavez, German, Cordova, Jesus H., Curo, Aleyda, Delgado, Amanda, Enciso, Marco A., Gutierrez, Roberto, Lehr, Edgar, Martinez, Jorge L., Medina-Muller, Margarita, Miranda, Alfonso, Neira, Daniel R., Ochoa, Jose A., Quiroz, Aaron J., Rodriguez, Daniel A., Rodriguez, Lily O., Salas, Antonio W., Seimon, Anton, Seimon, Tracie, Siu-Ting, Karen, Suarez, Juana, Torres, Claudia, Twomey, Evan, von May, Rudolf   +26 more
core   +1 more source

Evolutionary interplay between viruses and R‐loops

FEBS Letters, EarlyView.
Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi, Zita Képes, Zoltán Szabó, Eszter Csoma, Lóránt Székvölgyi   +4 more
wiley   +1 more source

Terrestrial mammal fauna and threatened species in France

Hystrix, the Italian Journal of Mammalogy, 1996
<strong>Abstract</strong> With the passing of time, the terrestrial mammal fauna changed considerably in France: definitive extinctions, temporary disappearances, natural reapparitions, introductions and reintroductions.
François De Beaufort, Hervé Maurin, Patrick Haffner   +2 more
doaj   +1 more source

Evidence that vulture restaurants increase the local abundance of mammalian carnivores in South Africa [PDF]

, 2014
Vulture restaurants are used worldwide as a conservation tool to provide threatened vultures with a source of supplementary carrion free from anthropogenic contaminants such as poisons and veterinary drugs.
Altizer, Bellan, Bino, Blaum, Carruthers, Cortés-Avizanda, Cortés-Avizanda, Craft, DeVault, Deygout, Deygout, Dijk, Donazar, Dyk, Fuller, Gilbert, Jhala, Kamler, Kolowski, Kortello, Kruuk, Loveridge, Markandya, Mateo-Tomas, Monadjem, Monello, Moreno-Opo, Mundy, Ogada, Ogada, Olson, Oro, Pain, Phipps, Phipps, Piper, Robb, Sekercioglu, St John, Stuart, Thorn, Thorn, Wilmers, Wilson, Wright, Yarnell, Yirga, Zulu   +47 more
core   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

At a global scale, do climate change threatened species also face a greater number of non-climatic threats?

Global Ecology and Conservation, 2017
For many species the threats of climate change occur in a context of multiple existing threats. Given the current focus of global change ecology in identifying and understanding species vulnerable to climate change, we performed a global analysis to ...
Lucas B. Fortini, Kaipo Dye
doaj   +1 more source

A global assessment of the drivers of threatened terrestrial species richness

Nature Communications, 2020
High numbers of threatened species might be expected to occur where overall species richness is also high; however, this explains only a proportion of the global variation in threatened species richness.
C. Howard, C. Flather, P. Stephens
semanticscholar   +1 more source

Advanced glycation end products promote the release of endothelial cell‐derived mitocytosis

FEBS Open Bio, EarlyView.
Under diabetic conditions, AGEs induce mitochondrial damage in HUVECs, activating migrasome‐mediated mitocytosis. Migrasomes encapsulate damaged mitochondria and are released into the extracellular space, facilitating intercellular mitochondrial transfer.
Rong Liu, Yuhao Zhang, Tiantian Ge, Hao Wu, Yongbin Ma, Honghua Ye, Fei Guo   +6 more
wiley   +1 more source