Results 61 to 70 of about 66,810 (264)

Available data and risk assessment of the Brazilian threatened species of Combretaceae

Rodriguésia
The risk assessment is made up of risk analyses of species extinction in a given time, following the International Union for Conservation of Nature and Natural Resources (IUCN) criteria.
Rafael Borges, Miguel d'Ávila de Moraes, Nina Pougy Monteiro, Ananda Meinberg Bevacqua, Gustavo Martinelli, Nilda Marquete   +5 more
doaj   +1 more source

An Aggregation‐Induced Polymerization Poly(Disulfide)‐Drug Nanoplatform for Autoimmune Uveitis Therapy via Inhibiting the cGAS‐STING Pathway

Advanced Science, EarlyView.
A cationic poly(disulfide)‐drug nanoplatform (LA/DexP) was developed to treat experimental autoimmune uveitis (EAU). With potent blood‐retinal barrier penetrability, LA/DexP releases DSP in response to high ROS and scavenges cfDNA to inhibit the cGAS‐STING signaling pathway.
Yuelan Wu, Wenbo Geng, Qinjin Dai, Wanyun Zhang, Yuxian Lai, Pei Zhang, Chunjiang Zhou, Yinuo Wang, Qingfeng Cao, Xiang Luo, Yujie Lai, Changwei Huang, Peizeng Yang   +12 more
wiley   +1 more source

Single–Atom Iron Sites Enable Enhanced Arsenic Removal From Water Through Synergistic Adsorption–Oxidation

Advanced Science, EarlyView.
Single–atom iron anchored on nitrogen–doped porous biochar exhibited ultra–efficient performance, exceptional environmental resilience, and integrated adsorption–oxidation functionality. The multifunctional architecture of the support and the unparalleled reactivity of single–atom iron underpinned the cooperative adsorption and oxidation of As(III ...
Tao Sun, Chao Wang, Shihang Wu, Xiaojia Zhou, Penggang Pei, Huijuan Yu, Yun Zhang, Qingqing Huang, Yuebing Sun   +8 more
wiley   +1 more source

The state of Nepal birds 2010

Journal of Threatened Taxa, 2013
The national status of Nepal birds was determined using the IUCN Red List criteria and following IUCN regional guidelines. Records of all species identified as potentially at high risk were extracted from all relevant references in a comprehensive, up ...
C. Inskipp, H.S. Baral, T. Inskipp, A. Stattersfield   +3 more
doaj   +1 more source

BCG HSP70 Reprograms Macrophages via Central Trained Immunity to Suppress Prostate Cancer

Advanced Science, EarlyView.
BCG‐derived HSP70 (Dnak) safely induces central trained immunity via epigenetic, metabolic, and O‐GlcNAcylation reprogramming of bone marrow progenitors, driving tumor‐associated macrophages toward an M1‐like phenotype to suppress prostate cancer. ABSTRACT Trained immunity offers a promising yet clinically challenging strategy for cancer immunotherapy,
Peng Liu, Kangkang Liu, Keruo Wang, Heyang Guan, Jiaming Fan, Taipeng Li, Jiaru Hao, Zeyuan Wang, Yongchao Yan, Jiatong Chen, Yuan Ma, Yang Yang, Yuanjie Niu   +12 more
wiley   +1 more source

Threatened pollinator and plant species in megadiverse countries: what we have learned from a synthesis of interactions for Brazil [PDF]

Anais da Academia Brasileira de Ciências
Plant-pollinator interactions are essential for the reproduction of most flowering plants and the maintenance of biodiversity. With each new assessment of threat status, new plants and pollinators are included in the list of threatened species.
LUCAS BENÍCIO DE CASTRO, RENON S. ANDRADE, PIETRO KIYOSHI MARUYAMA, ISABELA G. VARASSIN, SARA STEFANI DOMINGOS, MARCIA M. MAUÉS, ANTONIO MAURO SARAIVA, JOSÉ SALIM, KAYNA AGOSTINI, MARINA WOLOWSKI, ONILDO J. MARINI-FILHO, LEANDRO FREITAS, ANDRÉ RODRIGO RECH   +12 more
doaj   +2 more sources

DDX3x Regulates NINJ1 Transcription via Histone Lactylation in Sepsis Associated‐Acute Kidney Injury

Advanced Science, EarlyView.
This study identifies a potential therapeutic approach for sepsis‐associated acute kidney injury (SA‐AKI). We found that during SA‐AKI, reduced expression of DDX3x in renal tubular epithelial cells mediates histone delactylation, which in turn upregulates NINJ1 transcription and triggers tubular cell death. Conversely, Odetiglucan confers protection by
Hongyu Liang, Jihong Jiang, Huanxin Yin, Chunyan Liu, Hongjun Huang, Yan Luo, Minmin Zhu, Qiuyun Wang   +7 more
wiley   +1 more source

Non-volant mammals of the Maracaju Mountains, southwestern Brazil: composition, richness and conservation

Revista Mexicana de Biodiversidad, 2015
We report the results of the non-volant mammal survey at the Maracaju Mountains located in the central region of Mato Grosso do Sul State, southwestern Brazil.
Wellington Hannibal, Maurício Neves-Godoi   +1 more
doaj   +1 more source

The Threatened Species Index: Tools Supporting Australia's Threatened Species Conservation

Up-to-date and comprehensive information on population trends is crucial for many aspects of conservation planning for Australia’s threatened species, including listing processes, prioritisation analyses, and designing and evaluating the impact of conservation actions.
McGrath, Sarah, Lawrie, Tayla, Heard, Geoffrey   +2 more
openaire   +1 more source

VlPAG/DRN Microglia Drive Neuropathic Pain‐Induced Depression via a Defined Neuroimmune Axis

Advanced Science, EarlyView.
Peripheral nerve injury (SNI) induces neuropathic pain, activates midbrain microglia, and triggers an NLRP3–IL‐1β–dependent inflammatory cascade. IL‐1β signals through IL‐1R1 on vlPAG/DRN VGLUT2+ neurons (vlPAG/DRNGlu), inducing hyperexcitability and driving the vlPAG/DRNGlu→BNSTGABA circuit to produce the affective component of neuropathic pain ...
Jing Yang, Bing‐Jie Tang, Jia‐Yi Li, Shu‐Lan Xie, Shumin Duan, Junping Chen, Shengmei Zhu, Zhen‐Zhong Xu   +7 more
wiley   +1 more source