Results 131 to 140 of about 271,704 (247)

Antagonistic Ubiquitin Switching by USP7 and RNF40 Orchestrates KDM6A Homeostasis to License Coronavirus Susceptibility

Advanced Science, EarlyView.
We identify an antagonistic ubiquitin circuit that controls cellular permissiveness to multiple coronaviruses. The deubiquitinase USP7 stabilizes the epigenetic regulator KDM6A to upregulate viral receptors, while the E3 ligase RNF40 degrades KDM6A by catalyzing K6/K11‐ubiquitin chains of KDM6A for autophagic degradation.
Meng‐Zhuo Huang, Zhong‐Yuan Yang, Shi Wang, Yan Ge, Lan Lin, Mia Madel Alfajaro, Renata B. Filler, Wan‐Yao Song, Ming‐Zhu Kong, Jin Wei   +9 more
wiley   +1 more source

Boundaries, Limits, Global Threats - How Can the Impacts of Global Synthetic Pollutants Be Reduced? [PDF]

Environ Sci Technol
Scheringer M, Arp HPH, Cousins IT.
europepmc   +1 more source

Spectral‐Integrated Thermal Absorption Model for Broadband Laser‐Protective Reflectors Under Supercontinuum Irradiation

Advanced Science, EarlyView.
A universal laser absorption model based on spectral integration enables the design of ultrabroadband dielectric multilayer reflectors for laser protection. The model reveals exponential decay of absorption characterized by two coefficients, and a design that prioritizes short‐wavelength reflection minimizes heating.
Yukang Feng, Yanzhi Wang, Yulin Zhang, Yesheng Lu, Yu Chen, Fanxin Meng, Huisong Hu, Zhongyang Xing, Jianda Shao   +8 more
wiley   +1 more source

How do you measure a threat in the air? Testing the universal, dynamic, and multifaceted nature of social identity threat. [PDF]

Sci Adv
Kroeper KM, Hernandez-Colmenares A, Green DJ, Williams HE, Kuzdal A, Ospina J, Moore CA, Agarwal G, Heckler AF, Crocker J, Fujita K, Murphy MC, Spencer SJ.   +12 more
europepmc   +1 more source

Parasitic Plant–Host Interactions: Molecular Mechanisms and Agricultural Resistance Strategies

Advanced Science, EarlyView.
Parasitic plants devastate global agriculture through sophisticated molecular interactions with host crops. This review synthesizes current understanding of parasitic plant‐host interactions, from strigolactone‐mediated germination and haustorium formation to host defense mechanisms.
Jiayang Shi, Qi Xie, Feifei Yu
wiley   +1 more source

DOTA‐grafted Cationic Polymers Behaving as Powerful Macromolecular Resistance‐reversal Agents (MRRAs) Combating Against New Delhi Metallo‐β‐lactamase (NDM)‐producing Bacteria

Advanced Science, EarlyView.
Two macromolecular resistance‐reversal agents (MRRAs)—linear (MRRAL) and nanostructured (MRRAN) polymers were fabricated by integrating DOTA motifs into tunable polycationic scaffolds. MRRAs exhibit superior antibacterial potency once combined with meropenem (MEM) through (i) bacterial membrane disruption via localized cationic charge and ...
Ruixue Wang, Jian Zhang, Yun li, Liping Qiao, Zhuorui Dong, Dandan Cui, Peirong Bai, Liping Li, Bing Cao, Ruiping Zhang   +9 more
wiley   +1 more source

Corrigendum to 'Microplastics and antibiotic resistance genes as rising threats: Their interaction represents an urgent environmental concern' Current Research in Microbial Sciences 9 (2025) 100447. [PDF]

Curr Res Microb Sci
Hongjin C, Rahman SU, Rehman A, Khan AA, Khalid M.   +4 more
europepmc   +1 more source

Tailored Organogel Systems for Optimized Pesticide Delivery: Mechanistic Insights and Agricultural Applications

Advanced Science, EarlyView.
Utilizing molecular engineering for network design, three pesticide‐loaded organogels (PLOs) carriers exhibiting varying degrees of flexibility were prepared. The mechanical properties of these carriers, tunable via their network molecular structures, enhance their structural adaptability and retention stability at biological interfaces, thereby ...
Yue Wang, SiYu Xv, Chao Wu, Nan Li, GuoPeng Teng, XuePing Huang, Jian Luo   +6 more
wiley   +1 more source

SecMLOps: A comprehensive framework for integrating security throughout the machine learning operations lifecycle. [PDF]

Empir Softw Eng
Zhang X, Zhao P, Jaskolka J, Li H, Lu R.
europepmc   +1 more source

Nanozymes for Energy and Environmental Sustainability

Advanced Science, EarlyView.
At present, the widely used nanozymes are oxidoreductase and hydrolase, which have proved to have great application prospects in energy and environment. ABSTRACT Nanozymes have shown remarkable promise in addressing pressing challenges in energy and environmental sustainability.
Xiaoqi Li, Jinxing Chen, Shaojun Dong
wiley   +1 more source