Results 121 to 130 of about 2,521,807 (266)

Cooler streets for a cycleable city: assessing policy alignment

Buildings & Cities
Non-communicable diseases are rising globally and require holistic responses to address the social and environmental determinants that shape health outcomes. Transport is one such determinant of health, and active transport (walking and cycling) has been
Crystal Tang, Judy Bush
doaj   +1 more source

Cybersecurity in Transportation Systems: Policies and Technology Directions [PDF]

arXiv
The transportation industry is experiencing vast digitalization as a plethora of technologies are being implemented to improve efficiency, functionality, and safety. Although technological advancements bring many benefits to transportation, integrating cyberspace across transportation sectors has introduced new and deliberate cyber threats. In the past,
arxiv  

Meisoindigo Acts as a Molecular Glue to Target PKMYT1 for Degradation in Chronic Myeloid Leukemia Therapy

Advanced Science, EarlyView.
Meisoindigo targets PKMYT1 for degradation by acting as a molecular glue that enhances PKMYT1‐TRIM25 interaction, leading to K48‐linked ubiquitination and subsequent proteasomal degradation, thereby exerting therapeutic effects in chronic myeloid leukemia.
Zhao‐Xin Zhang, Shu‐Ying Li, Fang‐Fei Li, Qin‐Yan Shi, Cheng‐Yong Tan, Xiao‐Jing Wang, Mi Li, Yun‐Bao Liu, Jing Jin, Yong Li, Shi‐Shan Yu   +10 more
wiley   +1 more source

A brief introduction to the United States CDC Laboratory Response Network for Chemical Threats

Zhongguo gonggong weisheng
The United States Centers for Disease Control and Prevention (CDC) Laboratory Response Network for Chemical Threats (LRN-C) is a network of more than 50 primarily local public health laboratories covering all states and regions of the United States.
Xuefei LENG, Yimin WEN
doaj   +1 more source

Dimethyl Itaconate Alleviates Escherichia coli‐Induced Endometritis Through the Guanosine‐CXCL14 Axis via Increasing the Abundance of norank_f_Muribaculaceae

Advanced Science, EarlyView.
The research findings indicate that dimethyl itaconate (DI) alleviates Escherichia coli (E. coli) induced endometritis by modulating the gut microbiota and enriching the abundance of norank_f_Muribaculaceae, thereby increasing the production of guanosine.
Yuhang He, Jiapei Cai, Xufeng Xie, Xinyu Zhang, Linkai Qu, Jiuxi Liu, Yongguo Cao   +6 more
wiley   +1 more source

Deep Learning‐Enhanced Hand‐Driven Microfluidic Chip for Multiplexed Nucleic Acid Detection Based on RPA/CRISPR

Advanced Science, EarlyView.
Efficient R‐CHIP HR‐HPV Screening System: The R‐CHIP system utilizes the RPA/CRISPR method, a hand‐driven centrifugal microfluidic device, a smartphone micro‐imaging system, and the ResNet‐18 deep‐learning algorithm to simplify the sample detection process, ensure accurate results, and reduce costs.
Tao Xu, Ying Zhang, Shunji Li, Chenxi Dai, Hongguo Wei, Dongjuan Chen, Yunjun Zhao, He Liu, Deliang Li, Peng Chen, Bi‐Feng Liu, Ye Tian   +11 more
wiley   +1 more source

FAULT TREE METHOD AS A DECISION-MAKING TOOL FOR ASSESSING THE RISKS OF TRANSPORTATION OF DANGEROUS LOADS

Scientific Journal of Silesian University of Technology. Series Transport
Improving road traffic safety on the one hand and increasing the transport of dangerous goods on the other requires searching for methods and tools for risk assessment at various levels of transport of this type of cargo.
M. Lasota, Marianna Jacyna, Lucyna Szaciłło   +2 more
semanticscholar   +1 more source

Mechanisms of Baicalin Alleviates Intestinal Inflammation: Role of M1 Macrophage Polarization and Lactobacillus amylovorus

Advanced Science, EarlyView.
Baicalin alleviates E. coli‐induced intestinal inflammation through dual mechanisms: direct inhibition of the TLR4/IRF/STAT signaling pathway to modulate macrophage polarization and antigen presentation, thereby regulating Th17/Treg cell differentiation; and microbiota‐mediated indirect effects via increasing Lactobacillus amylovorus abundance and ...
Shunfen Zhang, Ruqing Zhong, Miao Zhou, Kai Li, Huiyuan Lv, Huixin Wang, Ye Xu, Dadan Liu, Qiugang Ma, Liang Chen, Hongfu Zhang   +10 more
wiley   +1 more source

A Reversible and Dynamic Surface Functionalization for Fluidity Controlled Multivalent Recognition of Lectins and Bacteria

Advanced Science, EarlyView.
A reversible wet chemical surface functionalization results in dynamic multivalent receptors showing ligand‐specific high affinity for lectins and bacteria. Abstract The paper reports the design of multivalent bacterial receptors based on reversible self‐assembled monolayers (rSAMs) on gold and glass substrates, mimicking the ligand display on host ...
Thomas Hix‐Janssens, Adam Tillo, Hanna Isaieva, Zita Lopes da Silva, Zahra Fatahi, Michele Larocca, Gustav Sedelius, Sara Björk Sigurdardóttir, Yulia Sergeeva, Tiba Al‐Dujaili, Julia R. Davies, Kushagr Punyani, Börje Sellergren   +12 more
wiley   +1 more source

Nanoparticle Delivery of Antisense miR162 Inhibits Invasive Habitat Adaption of Alternanthera Philoxeroides

Advanced Science, EarlyView.
This study demonstrates that the miRNA pathway plays a key role in the invasive growth of Alternanthera philoxeroides in aquatic habitats. Specifically, miR162 is critical for its invasive success, facilitating stem elongation and enhancing survival during submergence.
Qianqian Hu, Erfeng Kou, Xiuzhen Liao, Ruiyi Qiu, Qi Tang, Huan Zhang, Yun Zheng, Ji Yang, Binglian Zheng   +8 more
wiley   +1 more source