Results 121 to 130 of about 346,865 (252)

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

Rapid and Direct Detection of Methamphetamine in Biofluids using a MXene‐Enabled Electrochemical Sensor

open access: yesAdvanced Science, EarlyView.
A MXene‐enhanced electrochemical sensor enables the rapid and direct detection of methamphetamine. Molecular simulations reveal that specific MXene surface functional groups act as key signal amplifiers by facilitating interfacial interactions. The sensor demonstrates high sensitivity and robust performance in complex biological matrices.
Ri Wang   +7 more
wiley   +1 more source

A Secure Privacy‐Preserving System for SDN‐Based VANET Using the AES‐ECDH Algorithm

open access: yesIET Networks
A Software‐Defined Network (SDN)‐based Vehicular Ad Hoc Network (VANET) plays a crucial role in Intelligent Transport Systems (ITS) by enhancing road safety for drivers and vehicles through the periodic exchange of messages and data related to traffic ...
Adi El‐Dalahmeh   +2 more
doaj   +1 more source

Deep Brain Stimulation Induces Antidepressant Effects by Restoring High‐Fidelity Communication in the BNST‐NAc Circuit

open access: yesAdvanced Science, EarlyView.
This cross‐species study reveals that pathological hyperactivity of BNST neurons in depressive states disrupts inhibitory period and isolated spikes in the BNST‐NAc circuit. DBS achieves its antidepressant effects by precisely restoring network inhibitory periods and high‐fidelity signal transmission.
Xin Lv   +12 more
wiley   +1 more source

2D Metal‐Organic Frameworks for High‐Performance Solid‐State Electrolytes: A Comprehensive Review

open access: yesAdvanced Science, EarlyView.
In this review, we elucidate the intrinsic advantages, synthetic methodologies, structural characteristics, ion‐transport mechanisms and performance optimization strategies while highlighting representative material systems and applications of 2D MOFs for electrolyte applications.
Changchun Ai   +8 more
wiley   +1 more source

Road-Development Strategies to Support Self-Drive Tourism (SDT) in Bali Based on SWOT Analysis

open access: yesJournal on Tourism & Sustainability, 2018
Self-drive tourism (SDT) has become a potential alternative of tourism in Bali, an island that has dozens of tourist attractions scattered all over it. Unfortunately, Bali still has an insufficient integrated system of land transportation. Tourists tend
Nicholas Marpaung, Tetsuo Shimizu
doaj  

Strategic capacities in Dutch water management and spatial planning [PDF]

open access: yes
Dutch water management currently is in a position of fundamental change and renewal. As a consequence of factors such as climate change, continuous land subsidence, urbanisation pressures, and a lacking natural resilience of the water system to absorb ...
Johan Woltjer, Niels Al
core  

An ATP‐Mediated Antibiotic β‐Peptide Nanofiber That Kills Multidrug‐Resistant Bacteria via a Multistage Mechanism

open access: yesAdvanced Science, EarlyView.
The 3K‐AP system forms infinite supramolecular fibrils that undergo controlled degradation into shorter fragments upon enzymatic hydrolysis. Multitechnique imaging reveals a stepwise bacteriolytic mechanism involving bacterial entrapment, disassembly into lethal constructs, and associated extracellular vesicle release, highlighting the dynamic ...
Sohini Chakraborty   +21 more
wiley   +1 more source

Multimodal Wearable Biosensing Meets Multidomain AI: A Pathway to Decentralized Healthcare

open access: yesAdvanced Science, EarlyView.
Multimodal biosensing meets multidomain AI. Wearable biosensors capture complementary biochemical and physiological signals, while cross‐device, population‐aware learning aligns noisy, heterogeneous streams. This Review distills key sensing modalities, fusion and calibration strategies, and privacy‐preserving deployment pathways that transform ...
Chenshu Liu   +10 more
wiley   +1 more source

Ownership concentration, market monitoring and performance: Evidence from the UK, the Czech Republic and Poland [PDF]

open access: yes
Using data for publicly traded companies from the UK and two transition countries, the Czech Republic and Poland, we analyze the relationship between ownership concentratio and performance while also accounting for the effect of hostile takeover threats ...
Mariana Spatareanu, Vahe Lskavyan
core  

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