Results 41 to 50 of about 772,789 (252)

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

General Relativistic Effect on Sitnikov Three-Body Problem: Restricted Case

open access: yesAstronomy
We investigate the effect of general relativity on the Sitnikov problem. The Sitnikov problem is one of the simplest three-body problems, in which the two primary bodies (a binary system) have equal mass m and orbit their barycenter, while the third body
Hideyoshi Arakida
doaj   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

O pluralismo da tese dos três mundos de Popper e a crítica de Habermas [PDF]

open access: yesPrincípios, 2006
The present study approaches the three world thesis (TWT), by Karl Popper. The TWT as pluralist and interactionist opposes to monism and some dualist conceptions.
João Batista C. Sieczkowski
doaj  

Analytic Understanding of the Resonant Nature of Kozai–Lidov Cycles with a Precessing Quadrupole Potential

open access: yesThe Astrophysical Journal Letters, 2023
The very long-term evolution of the hierarchical restricted three-body problem with a slightly aligned precessing quadrupole potential is studied analytically.
Ygal Y. Klein, Boaz Katz
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

open access: yesFEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill   +4 more
wiley   +1 more source

How phagocytic cells kill bacteria: Lessons from a professional killer

open access: yesFEBS Open Bio, EarlyView.
How phagocytic cells ingest and kill bacteria has been studied for more than a century, but many questions remain unanswered. The study of the amoeba Dictyostelium discoideum brings new answers, and new questions. Professional phagocytic cells such as neutrophils and macrophages, as well as free‐living soil amoebae like Dictyostelium discoideum, employ
Otmane Lamrabet, Pierre Cosson
wiley   +1 more source

Pathways and pitfalls: a qualitative study of student experiences in biomedical science education

open access: yesFEBS Open Bio, EarlyView.
Biomedical science students from underrepresented backgrounds face barriers including financial strain, disrupted laboratory access and cultural exclusion. Peer networks provide vital support when institutional systems are difficult to navigate. To create inclusive learning environments and achieve academic success, educators should blend active, hands‐
Olivia J. Russell   +8 more
wiley   +1 more source

The Electromagnetic Three-Body Problem With Radiation Terms - Derivation of Equations of Motion (I)

open access: yesResults in Nonlinear Analysis, 2020
The primary purpose of the present paper is to continue the previous investigations of the author and apply the technique from the two-body problem of classical electrodynamics to the three-body problem.
Vasil G. Angelov
doaj  

Rendezvous and Proximity Operations in Cislunar Space Using Linearized Dynamics for Estimation

open access: yesAerospace, 2023
As interest in Moon exploration grows, and efforts to establish an orbiting outpost intensify, accurate modeling of spacecraft dynamics in cislunar space is becoming increasingly important.
David Zuehlke   +3 more
doaj   +1 more source

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