Results 41 to 50 of about 19,332,899 (233)
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
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Dynamical Structures under Nonrestricted Hierarchical Planetary Systems with Different Mass Ratios
The Astronomical JournalSecular dynamics have been extensively studied in both the inner and outer restricted hierarchical three-body systems. In the inner restricted problem, the quadrupole-order resonance (i.e., the well-known Kozai resonance) causes large coupled ...
Xiumin Huang, Hanlun Lei
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
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General Relativistic Effect on Sitnikov Three-Body Problem: Restricted Case
AstronomyWe investigate the effect of general relativity on the Sitnikov problem. The Sitnikov problem is one of the simplest three-body problems, in which the two primary bodies (a binary system) have equal mass m and orbit their barycenter, while the third body
Hideyoshi Arakida
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Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
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Stabilizing periodic orbits above the elliptic plane in the solar sail 3-body problem [PDF]
, 2008 We consider periodic orbits high above the ecliptic plane in the Elliptic Restricted Three-Body Problem where the third massless body is a solar sail.
Biggs, J.D., McInnes, C., Waters, T.
core +2 more sources
O pluralismo da tese dos três mundos de Popper e a crítica de Habermas [PDF]
Princípios, 2006 The present study approaches the three world thesis (TWT), by Karl Popper. The TWT as pluralist and interactionist opposes to monism and some dualist conceptions.
João Batista C. Sieczkowski
doaj
The Astrophysical Journal Letters, 2023 The very long-term evolution of the hierarchical restricted three-body problem with a slightly aligned precessing quadrupole potential is studied analytically.
Ygal Y. Klein, Boaz Katz
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MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source