Results 111 to 120 of about 3,351,684 (327)
The IFNγ‐CIITA‐MHC II axis modulates melanoma cell susceptibility to NK‐cell‐mediated cytotoxicity
Molecular Oncology, EarlyView.Natural killer (NK) cells play a central role in anti‐melanoma immunity. However, melanoma cells adapt during co‐culture by upregulating CIITA and MHC II in response to interferon gamma (IFNγ), thereby evading NK‐cell lysis. Blocking IFNγ signaling or treatment with dimethyl fumarate/simvastatin counteracts this immune escape and maintains NK‐cell ...
Lena C. M. Krause +6 more
wiley +1 more source
A Hollerith technique for computing three-dimensional differential Fourier synthesis in X-ray crystal-structure analysis [PDF]
, 1949 Ε. G. Cox, Leona Gross, G. A. Jeffrey
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On three-dimensional coupled bosons [PDF]
Journal of Mathematical Physics, 2002 In this work we study two complex scalar fields coupled through a quadratic interaction in 2+1 dimensions using the method of bilinears as suggested by Rajeev [Int. J. Mod. Phys. A 9, 5583 (1994)]. The resulting theory can be formulated as a classical theory. We study the linear approximation, and show that there is a possible bound state in a range of
openaire +4 more sources
FEBS Open Bio, EarlyView.Cleavable N‐terminal Thioredoxin fusion enabled soluble expression and purification of otherwise insoluble SARS‐CoV‐2 Nucleocapsid (N) protein. A four‐step purification strategy yielded highly homogeneous, RNA‐free N protein. Binding assays showed high RNA affinity (Kd ~ 28 nm). The study will facilitate high‐resolution structural studies of N protein,
Shweta Singh, Gagan D. Gupta
wiley +1 more source
FEBS Open Bio, EarlyView.In Thermus thermophilus, more than half of the phosphorylation sites identified by proteomic analysis are located near the active site. All phosphomimetic mutants of phosphosites of six enzymes belonging to different families showed severely reduced activity compared with the wild‐type, particularly in the turnover number.
Anzu Nishiwaki +3 more
wiley +1 more source
Fracture and Structural Integrity, 2013 The paper deals with the three-dimensional nature and the multi-parametric representation of the stress field ahead of cracks and notches of different shape. Finite thickness plates are considered, under different loading conditions.
P. Lazzarin, M. Zappalorto, F. Berto
doaj
Discussion: “Three-Dimensional Solution for Stress Concentration Around a Circular Hole in a Plate of Arbitrary Thickness” (Sternberg, E., and Sadowsky, M. A., 1949, ASME J. Appl. Mech., 16, pp. 27–38) [PDF]
, 1950 M. M. Frocht
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FEBS Open Bio, EarlyView.Under environmental changes, the expression level of neuropeptide (NP) and neuropeptide receptor (NPR) genes changes to confer context‐dependent adaptation to the model organism Drosophila melanogaster. Through finding more regulatory elements in the NPR genes in comparison with their ligands (NPs), we found that NPR‐biased transcriptional regulation ...
SeungHeui Ryu +6 more
wiley +1 more source
On Three-Dimensional Space Groups
, 1999 An entirely new and independent enumeration of the crystallographic space groups is given, based on obtaining the groups as fibrations over the plane crystallographic groups, when this is possible.
Conway, John +3 more
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