Results 81 to 90 of about 14,312,962 (297)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

Transthoracic three-dimensional echocardiography for the assessment of straddling tricuspid or mitral valves [PDF]

open access: yes, 2000
Background The advent of 3D echocardiography has provided a technique which, potentially, could afford significant additional information over conventional cross-sectional echocardiography in the assessment of patients with straddling atrioventricular ...
Anderson, RH   +3 more
core  

Three-Dimensional Digital Zooming of Integral Imaging under Photon-Starved Conditions

open access: yes, 2023
In this paper, we propose new three-dimensional (3D) visualization of objects at long distance under photon-starved conditions. In conventional three-dimensional image visualization techniques, the visual quality of three-dimensional images may be ...
Myungjin Cho, Gilsu Yeo
core   +1 more source

Asymmetrical Three-Dimensional Conformal Imaging Lens

open access: yesPhotonics
Absolute instrument refers to a media that can make light rays to propagate in a closed orbit and perform imaging and self-imaging. In the past few decades, traditional investigations into absolute instrument have been centered on the two-dimensional ...
Desen Gong   +3 more
doaj   +1 more source

Spatial biology in cancer epigenetics

open access: yesMolecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

MaXIMA - Three dimensional breast cancer models for X-ray Imaging research

open access: yes, 2016
The development of realistic three-dimensional computational and physical models of breast tumours with irregular shapes and their availability is a powerful instrument in the hands of engineers, physicians and physicists to be used in the development of
Francesca Di Lillo   +3 more
core  

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

open access: yesMolecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault   +12 more
wiley   +1 more source

Prediction Of Suitable Lip Support With Nasolabial Angle Edentulous Patients

open access: yesInternational Dental Journal
Aim or purpose: The present investigation aims to investigate the correlation between lip fullness and lip support and to explore a virtual prediction method for suitable lip support in Chinese edentulous patients Materials and methods: A series of ...
You Lang
doaj   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

open access: yesFEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz   +6 more
wiley   +1 more source

Synthetic aperture sonar imaging using compressive sensing and an ultrasound transducer array [PDF]

open access: yes, 2013
Includes bibliographical references.Compressive sensing (CS) also known as compressive sampling is a technique used to reconstruct or recover the full-length of a signal with only a few non-adaptive measurements.
Jideani, Josiah Chimnanu
core   +1 more source

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