Results 151 to 160 of about 24,812,873 (248)

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

FEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain, Elise Buret, Le Hoang Thanh Nguyen, Marion Cocheteux, Nicolas Touya, Mélanie Dhayer, Romain Dubois, Frank Lafont, Sebastien Janel, Patrice Maboudou, Steve Lancel, Philippe Marchetti   +11 more
wiley   +1 more source

Disentangling Counter-Empathy: Developing a Three-Dimensional Model and Measure of Dispositional Counter-Empathy. [PDF]

J Pers
Siamro JR, Jordan CH.
europepmc   +1 more source

Liver organoids: a promising three-dimensional model for insights and innovations in tumor progression and precision medicine of liver cancer. [PDF]

Front Immunol, 2023
Chen Y, Liu Y, Chen S, Zhang L, Rao J, Lu X, Ma Y.   +6 more
europepmc   +1 more source

Structural and biochemical insights into the thermostable esterase Ta0887 from Thermoplasma acidophilum

FEBS Open Bio, EarlyView.
In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey, Miriam Livier Llamas‐García, Gabriela M. Montero‐Morán, Leticia Santos, Samuel Lara‐González   +4 more
wiley   +1 more source

How to create a virtual and printed three-dimensional model of a complex fistula-in-ano. [PDF]

ANZ J Surg
Ruscoe Z, Lin C, Kokelaar R, Yeung JM, Shannon R.   +4 more
europepmc   +1 more source

Development of an implantable three-dimensional model of a functional pathogenic multispecies biofilm to study infected wounds. [PDF]

Sci Rep, 2022
Cárdenas-Calderón C, Veloso-Giménez V, González T, Wozniak A, García P, Martín SS, Varas JF, Carrasco-Wong I, Vera M, Egaña JT.   +9 more
europepmc   +1 more source

Cell surface CD11c as a neutrophil aging marker molecule

FEBS Open Bio, EarlyView.
Cell surface CD11chi neutrophils were more aged and had better phagocytic function than CD11c−/lo neutrophils. Transcriptomic analysis of CD11chi neutrophils and CD11c−/lo neutrophils in pediatric population showed that the most difference was seen in infants.
Sophia Koutsogiannaki, Fahd Alhamdan, Erik Malm, Marie Bermudez, Samuel Y. Kim, Koichi Yuki   +5 more
wiley   +1 more source

A vascularized three-dimensional model integrating primary breast tumor cells and microvascular fragments: mimicking the tumor microenvironment involved in chemoresistance. [PDF]

Cancer Cell Int
Lo Cicero A, La Monica F, Lo Buglio G, Campora S, Gangemi F, Cinà P, Salamone M, Lo Pinto M, Scilabra SD, Ghersi G.   +9 more
europepmc   +1 more source

A novel MRI-based three-dimensional model of stomach volume, surface area, and geometry in response to gastric filling and emptying. [PDF]

Neurogastroenterol Motil, 2023
Bertoli D, Mark EB, Liao D, Brock C, Frøkjaer JB, Drewes AM.   +5 more
europepmc   +1 more source

BCG vaccination potentiates oxidative phosphorylation in neonatal myeloid‐derived suppressor cells

FEBS Open Bio, EarlyView.
BCG vaccination enhances oxidative phosphorylation in neonatal MDSCs, impairing their immunosuppressive function. It upregulates electron transport chain genes and mitochondrial activity, increasing ATP and oxygen consumption. Pharmacological OXPHOS inhibition partially restores suppressive capacity, confirming causality.
Yingying Chen, Hui Li
wiley   +1 more source