Results 51 to 60 of about 13,281,117 (305)
Veterinary Medicine and Science, 2021 Background The cellular mechanisms involved in the development of proximal tubules are not only associated with morphogenesis in fetal life, but also with restoration of damaged tubules in adulthood.
Jing Cong +8 more
doaj +1 more source
Molecular Oncology, EarlyView.The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka +9 more
wiley +1 more source
, 2019 a) three-dimensional Z stack (13 frames, 1 μm/step) reconstruction of SRS images at 2,845 cm-1; b) three-dimensional reconstruction of SRS images at 2,940 cm-1; c) three-dimensional reconstruction of simultaneous lipids and proteins distribution. All the
Daniela Corda (259902) +5 more
core +1 more source
Molecular Oncology, EarlyView.Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim +3 more
wiley +1 more source
Pliocene three-dimensional global ocean temperature reconstruction [PDF]
Climate of the Past, 2009 The thermal structure of the mid-Piacenzian ocean is obtained by combining the Pliocene Research, Interpretation and Synoptic Mapping Project (PRISM3) multiproxy sea-surface temperature (SST) reconstruction with bottom water temperature estimates from 27
H. J. Dowsett +2 more
doaj
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
A three-dimensional hydro-environmental model of Dublin Bay [PDF]
, 2011 This paper compares a 3-dimensional hydro-ecological model with a 2-dimensional model simulating the distribution and fate of Escherichia Coli (E.Coli) discharges from a sewage treatment plant discharging into Dublin Bay, Ireland. Before being discharged,
Dowley, Aodh +7 more
core +1 more source
Spatial biology in cancer epigenetics
Molecular Oncology, EarlyView.Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley +1 more source
Three Dimensional Image Reconstruction Based on KSVD for Electrical Capacitance Tomography
Journal of Harbin University of Science and Technology, 2020 ECT (Electrical Capacitance Tomography)is one of the effective methods to measure the parameters of twophase flow The threedimensional image reconstruction of capacitance tomography is a sensor system based on multilayer electrode structure A new ...
WANG Yunran, CHEN Deyun, WANG Lili
doaj +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source