Results 201 to 210 of about 5,789,762 (249)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Biomechanical Effects on the Prostheses and Vertebrae of Three-Level Hybrid Surgery: A Finite Element Study. [PDF]

Orthop Surg
Huang K, Wang Q, Rong X, Wu T, Ding C, Meng Y, Yin W, Liu H, Wang B.   +8 more
europepmc   +1 more source

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Overloaded Vertebral Body Following Consecutive Three-Level Hybrid Surgery Comparing with Anterior Cervical Discectomy and Fusion. [PDF]

Orthop Surg
Chen SH, Li YL, Liu H, Wu TK, Huang KK, Yao MH, Wang BY.   +6 more
europepmc   +1 more source

A Multi-Center Study on the Implementation and Challenges of Nursing Three-Level Ward Rounds in Tertiary Hospitals in Shanxi Province. [PDF]

J Multidiscip Healthc
Shao Y, Li Q, Bian M, Wang Y, Zhang X.
europepmc   +1 more source

A three-level regulatory mechanism of the aldo-keto reductase subfamily AKR12D. [PDF]

Nat Commun
Xiao Z, Zha J, Yang X, Huang T, Huang S, Liu Q, Wang X, Zhong J, Zheng J, Liang R, Deng Z, Zhang J, Lin S, Dai S.   +13 more
europepmc   +1 more source

Enhanced direct torque control based on intelligent approach for doubly-fed induction machine fed by three-level inverter. [PDF]

Heliyon
Moussaoui A, Ben Attous D, Benbouhenni H, Bekakra Y, Nedjadi B, Elbarbary ZMS.   +5 more
europepmc   +1 more source

Factors affecting blood sugar changes in diabetic patients using a three-level model in analysis of longitudinal data. [PDF]

Caspian J Intern Med
Rohani T, Hajian-Tilaki K, Hajiahmadi M, Heidari B, Rahimi Rahimabadi N, Geraili Z.   +5 more
europepmc   +1 more source