Results 61 to 70 of about 74,255 (306)

Integrated genomic and proteomic profiling reveals insights into chemoradiation resistance in cervical cancer

open access: yesMolecular Oncology, EarlyView.
A comprehensive genomic and proteomic analysis of cervical cancer revealed STK11 and STX3 as a potential biomarkers of chemoradiation resistance. Our study demonstrated EGFR as a therapeutic target, paving the way for precision strategies to overcome treatment failure and the DNA repair pathway as a critical mechanism of resistance.
Janani Sambath   +13 more
wiley   +1 more source

Constrained Modulated Model Predictive Control for a Three-Phase Three-Level Voltage Source Inverter

open access: yesIEEE Access, 2022
In the last decade, model predictive control (MPC) has been widely studied in power converters, such as voltage source inverters (VSIs). Unfortunately, MPC often presents a high computational burden that limits their applicability, especially when ...
Josue Andino   +5 more
doaj   +1 more source

Inhibition of CDK9 enhances AML cell death induced by combined venetoclax and azacitidine

open access: yesMolecular Oncology, EarlyView.
The CDK9 inhibitor AZD4573 downregulates c‐MYC and MCL‐1 to induce death of cytarabine (AraC)‐resistant AML cells. This enhances VEN + AZA‐induced cell death significantly more than any combination of two of the three drugs in AraC‐resistant AML cells.
Shuangshuang Wu   +18 more
wiley   +1 more source

Simulation of a Certain EMUs Using Three-level Inverter Based on SVPWM

open access: yes机车电传动, 2011
Main circuit of a certain EMUs using three-level inverter was introduced, control principle of space voltage vector SVPWM was analysesed in detail. Three-level inverter model based on SVPWM control was established and simulated by Matlab/Simulink.
蒲思培, 杨美传, 陆强
doaj  

Performance Analysis of an Optimized Asymmetric Multilevel Inverter on Grid Connected SPV System

open access: yesEnergies, 2022
The purpose of this research is to develop an efficient single-phase grid-connected PV system using a better performing asymmetrical multilevel inverter (AMI).
Devineni Gireesh Kumar   +9 more
doaj   +1 more source

Comparison of Induction and PM Synchronous motor drives for EV application including design examples [PDF]

open access: yes, 2012
Three different motor drives for electric traction are compared, in terms of output power and efficiency at the same stack dimensions and inverter size. Induction motor (IM), surface-mounted permanent-magnet (PM) (SPM), and interior PM (IPM) synchronous ...
Boazzo, Barbara   +3 more
core   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

open access: yesMolecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié   +16 more
wiley   +1 more source

A three-level MOSFET inverter for low power drives [PDF]

open access: yesIEEE 2002 28th Annual Conference of the Industrial Electronics Society. IECON 02, 2003
This paper proposes operating a three-level neutral-point-clamped (NPC) inverter using a two-level pulsewidth-modulation method. This allows for the clamping diodes to be rated at a fraction of the main switches due to their low average current requirement.
B.A. Welchko   +2 more
openaire   +1 more source

Implementing SVPWM Technique to an Axial Flux Permanent Magnet Synchronous Motor Drive with Internal Model Current Controller [PDF]

open access: yes, 2010
This paper presents a study of axial flux permanent magnet synchronous motor (AFPMSM) drive system. An internal model control (IMC) strategy is introduced to control the AFPMSM drive through currents, leading to an extension of PI control with ...
Darba, Araz   +2 more
core   +2 more sources

Glycosylated LGALS3BP is highly secreted by bladder cancer cells and represents a novel urinary disease biomarker

open access: yesMolecular Oncology, EarlyView.
Urinary LGALS3BP is elevated in bladder cancer patients compared to healthy controls as detected by the 1959 antibody–based ELISA. The antibody shows enhanced reactivity to the high‐mannose glycosylated variant secreted by cancer cells treated with kifunensine (KIF).
Asia Pece   +18 more
wiley   +1 more source

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